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Hospital register of patients with acute cerebrovascular accident (REGION): characteristics of patient and outcomes of hospital treatment

https://doi.org/10.15829/1728-8800-2018-6-32-38

Abstract

Aim. To assess the characteristics of patients and short-term outcomes of the disease in patients hospitalized for cerebral stroke (CS) based on the REGION-Moscow register.

Material and methods. From 2012 to 2017, 900 patients were included in the REGION-Moscow register, who were consecutively admitted to one of the clinics in Moscow, and in whom CS or transient ischemic attack (TIA) were diagnosed during hospitalization.

Results. The average age of the entire cohort of patients was 71±15 years. Women were 59,4%, men — 40,6%. The average age of women was 7 years more than the average age of men. Cardiovascular risk factors or a combination of them were detected in most patients. About 75% of CS were ischemic, 10% — hemorrhagic, 2% — mixed type, 13% were transient ischemic attack. Hospital mortality on average over the 5 years were 24,0%. There was a sharp increase in hospital mortality in 2014, which coincided with the organization of the vascular center, in subsequent years there was a progressive decrease in hospital mortality.

Conclusion. The development of CS in most patients was predictable and determined mainly by the presence of cardiovascular risk factors or a combination of them. Organization of the vascular center led to a gradual decrease in hospital mortality.

Boytsov S. A.5 on behalf of the working group.

REGION-Moscow register working group: Akimova A. V., Arutyunov G. P., Belova E. N., Blagodatskikh S. V., Boytsov S. A., Vernohaeva A. N., Viskov R. V., Voronina V. P., Gladilkina M. P., Deev A. D., Dmitrieva N. A., Drapkina O. M. Zagrebelny A. V., Kvitivadze G. K, Klyashtorny V. G., Kokareva I. V. , Kudryashov E. V., Kutishenko N. P., Lerman O. V., Lukyanov M. M., Martsevich S. Yu., Matveyeva A. D., Matskevich L. A., Mitichkin A. E., Nikitina G. I., Nikoshnova E. S. Ovsepyan M. A., Okshina E. Yu., Palamarchuk V. N., Parsadanyan N. E., Porezanova M. V., Sementsov D. P, Stakhovskaya L. V., Stepina E. V., Stolboushkina E. A., Halaeva M. A., Chernyshova M. I., Shamalov N. A.


About the Authors

S. Yu. Martsevich
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation
Moscow


N. P. Kutishenko
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


M. M. Lukyanov
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


A. V. Zagrebelny
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


N. A. Dmitrieva
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


E. Yu. Okshina
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


A. V. Akimova
ФГБУ “Национальный медицинский исследовательский центр профилактической медицины” Минздрава России
Russian Federation
Moscow


V. P. Voronina
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation

Moscow



O. V. Lerman
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation

Moscow



M. P. Gladilkina
F. I. Inozemtsev City Polyclinic
Russian Federation

Moscow



G. I. Krasnikova
F.I. Inozemtsev City Polyclinic
Russian Federation

Moscow



V. N. Palamarchuk
F.I. Inozemtsev City Polyclinic
Russian Federation

Moscow



N. E. Parsadanyan
City Polyclinic № 64
Russian Federation

Moscow



M. I. Chernyshova
City Polyclinic № 64
Russian Federation

Moscow



E. N. Belova
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation

Moscow



E. V. Kudryashov
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation

Moscow



N. A. Shamalov
N.I. Pirogov Russian National Research Medical University
Russian Federation

Moscow



G. P. Arutyunov
N.I. Pirogov Russian National Research Medical University
Russian Federation

Moscow



O. M. Drapkina
National Medical Research Center for Preventive Medicine of the Ministry of Health
Russian Federation

Moscow



S. A. Boytsov
National medical research center of cardiology
Russian Federation

Moscow



References

1. Benjamin EJ, Blaha MJ, Chiuve SE, et al. Heart Disease and Stroke Statistics 8. 2017 Update: A Report From the American Heart Association. Circulation. 2017;135(10):e146-603. doi:10.1161/CIR.0000000000000485.

2. Boytsov SA, Martsevich SY, Ginzburg ML, et al. Lyubertsy study on mortality rate in patients after cerebral stroke or transient ischemic attack (LIS-2). Design and medical treatment estimation. Rational Pharmacotherapy in Cardiology. 2013;9(2):114-22. (In Russ.) doi:10.20996/1819-6446-2013-9-2-114-122.

3. Popov VV, Khasanova NM, Sharashova EE, et al. Prevalence and dynamics of morbidity, mortality, lethality in acute cerebrovascular diseases in Arkhangelsk residents. Human ecology. 2011;7:48-54. (In Russ.)

4. Chugunova SA, Nikolaeva TY, Kuzmina ZM, et al. Stroke epidemiology in Yakutsk based on the population-based register in 2015. Far East Medical Journal. 2017;3:80-5. (In Russ.)

5. Skvortsova VI, Shetova IM, Kakorina EP, et al. Reduction in stroke death rates through a package of measures to improve medical care for patients with vascular 13. diseases in the Russian Federation. The Russian Journal of Preventive Medicine. 2018;21(1):4-10. (In Russ.) doi: 10.17116/profmed20182114-10.

6. Boytsov SA, Martsevich SY, Kutishenko NP, et al. The study “Register of Patients after Acute Stroke (REGION)”. Part 1. Hospital Prospective Register of Patients after Acute Stroke (According to the Results of the Pilot Phase of the Study). Rational Pharmacotherapy in Cardiology. 2016; 12(6):645-53. (In Russ.) doi:10.20996/1819-6446-2016-12-6-645-653.

7. Kotova EY, Mashin VV. Epidemiology and major risk factors for the development of stroke in Ulyanovsk (according to the register of stroke). Ulyanovsk medico-biological journal. 2011;2:100-7. (In Russ.)

8. Lebedev IA, Anishchenko LI, Akinina SA, et al. Clinical-epidemiological particularities of cerebral stroke in the Khanty-Mansijsk Autonomous District (in accordance to a population register). The Russian Military Medical Academy reporter. 2011;3:103-7. (In Russ.)

9. Kim D, Lee SH, Kim JB, et al. Secondary prevention by stroke subtype: a nationwide follow-up study in 46 108 patients after acute ischaemic stroke. Eur Heart J. 2013;34(35):2760-7. doi:10.1093/eurheartj/eht185.

10. O'Donnell MJ, Xavier D, Liu L, et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet. 2010;376(9735):112-23. doi:10.1016/S0140-6736(10)60834-3.

11. Slyusar ТА, Yakovlev NА, Аbramenko YV, et al. Stroke epidemiology in Verkhnevolzhie. S. S. Korsakov Journal of Neurology and Psychiatry (Stroke). 2007;210-11. (In Russ.)

12. Kachemaeva OB, Borisova NA. Epidemiological characteristics of stroke in Ufa, according to the register. Neurological herald them Bekhterev. 2007;39(1):45-8. (In Russ.)

13. Khutieva LS, Efremov VV. Clinical and epidemiological characteristics and stroke risk factors in Ingushetia. New technologies. 2012;1:234-9. (In Russ.)

14. Martsevich SY, Ginsburg ML, Kutishenko NP, et al. LIS Study (Lyubertsy Study of mortality in patients after acute myocardial infarction): the patients' portrait. Cardiovascular Therapy and Prevention. 2011;10(6):89-93. (In Russ.)

15. Martsevich SY, Kutishenko NP, Suvorov AY, et al. Characteristics of patients with cerebral stroke or transient ischemic attack, included into the LIS-2 register (Lyubertsy study of mortality in patients after stroke). Rational Pharmacotherapy in Cardiology 2015; 11 (1): 18-24. (In Russ.)

16. Langhorne P, O'Donnell MJ, Chin SL, et al. Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study. Lancet. 2018;391:2019-27. doi: 10.1016/S0140-6736(18)30802-X.


Review

For citations:


Martsevich S.Yu., Kutishenko N.P., Lukyanov M.M., Zagrebelny A.V., Dmitrieva N.A., Okshina E.Yu., Akimova A.V., Voronina V.P., Lerman O.V., Gladilkina M.P., Krasnikova G.I., Palamarchuk V.N., Parsadanyan N.E., Chernyshova M.I., Belova E.N., Kudryashov E.V., Shamalov N.A., Arutyunov G.P., Drapkina O.M., Boytsov S.A. Hospital register of patients with acute cerebrovascular accident (REGION): characteristics of patient and outcomes of hospital treatment. Cardiovascular Therapy and Prevention. 2018;17(6):32-38. (In Russ.) https://doi.org/10.15829/1728-8800-2018-6-32-38

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)