Antihypertensive effects of ACE inhibitor perindopril: ASCOT-BLPA Study lessons
Abstract
Antihypertensive effects of an ACE inhibitor perindopril were analyzed. In ASCOT-BPLA Study, blood pressure (BP) level for amlodipine ± perindopril treatment was lower than for atenolol ± bendroflumethiazide treatment (mean difference 2.7/1.9 mm Hg). Maximal BP difference was 5.9/2.4 mm Hg, by Month 3 of the therapy. Results of large-scale studies, confirming perindopril high efficacy and safety in arterial hypertension patients, were presented.
About the Author
Yu. M. Lopatin
Volgograd State Medical University, Volgograd Regional Cardiology Center. Volgograd
Russian Federation
Russian Federation
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Review
For citations:
Lopatin Yu.M. Antihypertensive effects of ACE inhibitor perindopril: ASCOT-BLPA Study lessons. Cardiovascular Therapy and Prevention. 2006;5(3):83-87. (In Russ.)
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