К ВОПРОСАМ ТЕЧЕНИЯ И ПРОГНОЗА КАРДИОВАСКУЛЯРНЫХ ЗАБОЛЕВАНИЙ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ

Статья посвящена вопросам, касающимся особенностей течения отдельных заболеваний сердечно-сосудистой системы у больных сахарным диабетом 2 типа (СД-2). Проведен обзор многоцентро­вых, клинических и экспериментальных исследований, где показа­но, что сопряженное течение СД способствует значимому увели­чению сердечно-сосудистой смертности в сравнении с больными без СД. Доказана взаимосвязь между гипергликемией, сократи­тельной функцией и электрической нестабильностью миокарда. При этом отмечены гендерные различия в течении сердечно-сосу­дистых заболеваний (ССЗ) при СД, а также прогнозе у больных. Вместе с тем, сохраняется ряд вопросов, касающихся клиниче­ской распространенности СД-2 среди больных ССЗ, течения отдельных нозологических форм (стабильная и нестабильная ише­мическая болезнь сердца, инфаркт миокарда, хроническая сер­дечная недостаточность) на фоне гипергликемии, особенностей прогноза больных ССЗ, сопряженных с СД, в т.ч. во взаимосвязи с полом. Малоизученными остаются также проблема нарушений ритма сердца у больных СД, а также влияние вида терапии на каче­ство и продолжительность жизни больных с коморбидными состо­яниями.

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