FOLLOWING THE PROBLEM OF PROGNOSIS AND COURSE OF CARDIOVASCULAR DISEASES AND DIABETES

The article takes into consideration the issues related to the specifics of clinical course of some cardiovascular diseases in diabetes mellitus patients 2nd type (DM2). The review of multicenter clinical and experimental studies has been done, where it was shown that comorbidity with DM leads to the significant increase of cardiovascular mortality comparing to those without DM. The interrelation of hyperglycemia, contractility and electrical instability of myocardium is shown. Also the gender differences are highlighted in clinical course, as in prognosis. By the way, some questions remain unanswered about clinical prevalence of DM2 among CVD patients, as about clinical course of some nosological forms (stable and unstable ischemic heart disease, myocardial infarction, chronic heart failure) at the background of hyperglycemia, specifics of CVD with DM prognosis, including gender specifics. Understudied are the problem of rhythm disorders in DM and the influence of therapy on quality and duration of life in patients with comorbidities.

The article takes into consideration the issues related to the specifics of clinical course of some cardiovascular diseases in diabetes mellitus patients 2nd type (DM2). The review of multicenter clinical and experimental studies has been done, where it was shown that comorbidity with DM leads to the significant increase of cardiovascular mortality comparing to those without DM. The interrelation of hyperglycemia, contractility and electrical instability of myocardium is shown. Also the gender differences are highlighted in clinical course, as in prognosis. By the way, some questions remain unanswered about clinical prevalence of DM2 among CVD patients, as about clinical course of some nosological

forms (stable and unstable ischemic heart disease, myocardial infarction,

chronic heart failure) at the background of hyperglycemia, specifics of

CVD with DM prognosis, including gender specifics. Understudied are

the problem of rhythm disorders in DM and the influence of therapy on

quality and duration of life in patients with comorbidities.

Key words: diabetes mellitus, cardiovascular diseases, complications,

prognosis.

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