Neurodynamics in young and middle-aged patients with arterial hypertension
Abstract
Aim. To evaluate neurodynamics parameters in young and middle-aged patients with arterial hypertension (AH).
Material and methods. In total, 41 men with AH (main group), aged 38-59 years, were examined. The control group included 15 healthy men (mean age 42,4+1,5 years). Interviewing, physical examination, and 24-hour blood pressure monitoring (BPM) were performed. Cognitive function was assessed with psycho-physiological program complex " Status PF", including neurodynamics tests (time of simple and complex visual-motor reactions - SVMR, CVMR).
Results. The results obtained verified cognitive dysfunction (CD) presence in young and middle-aged AH patients. At the same time, the interrelation between AH stage, AH duration and cognitive dysfunction type was U-shaped. The maximal CD was observed in individuals with AH duration <1 year or >10 years. Optimal cognitive function, possibly due to adaptation mechanisms, was detected in patients with AH duration of 5-10 years or in those aged 40-50 years. Inadequate BP decrease during nighttime was also associated with CD.
Conclusion. CD in AH was observed not only in elderly patients, but also in young and middle-aged persons with early AH stages. The changes in latent time of psycho-motor reactions could be regarded as the first manifestation of neurodynamics disturbances.
About the Authors
S. A. Smakotina
Kemerovo State Medical Academy, Ministry of Health and Social Development
Russian Federation
Russian Federation
O. A. Trubnikova
Kemerovo Region Clinical Hospital. Kemerovo
Russian Federation
Russian Federation
O. L. Barbarash
Kemerovo State Medical Academy, Ministry of Health and Social Development
Russian Federation
Russian Federation
References
1. Кобалава Ж.Д., Терещенко С.Н., Калинкин А.Л. Суточное мониторирование артериального давления: методические аспекты и клиническое значение. Москва 1997; 11с.
2. Котовская Ю.Т., Кобалава Ж.Д., Лобанкова Л.А., Толкачева В.В. Диспропорциональность суточного ритма артериального давления у больных артериальной гипертонией и сахарным диабетом типа 2. Артер гиперт 2003; 2: 59-63.
3. Остроумова О.Д., Корсакова Н.К., Баграмова Ю.А., Варако Н.А. Артериальная гипертензия и сосудистая деменция: влияние гипотензивной терапии у пожилых больных (клинические и фармакологические аспекты). Cons med 2006; 5(5): 261-4.
4. Рязанов А.С., Аракелянс А.А., Юренев А.П. Гипертоническое сердце. Состояние проблемы. Клин мед 2003; 6: 15-8.
5. Шляхто Е.В., Конради А.О., Захаров Д.В., Рудоманов О.Г. Структурно-функциональные изменения миокарда у больных гипертонической болезнью. Кардиология 1999; 2: 49-55.
6. Bowen J., Teri L., Kukull W. et al. Progression to demen tia in patients with isolated memory loss.
7. Frisoni G.B., Galluzzi S., Bresciani L. et al. Mild cognitive impairment with subcortical vascular features. Clinical characteristics and outcome. J Neurol 2002; 249: 1423-32.
8. Ikeda M. Prevention and early intervention for vascular dementia in community dwelling elderly: Findings from the Nakayama study. Psychogeriatrics 2003; 3: 17-20.
9. Rockwood K., Black S., Feldman H. Progression to dementia in patients with vascular cognitive impairment without dementia: a multi-centre clinical study. In: 2nd Congress of the International Society for Vascular Behavioural and Cognitive Disorders (Vas-Cog). Abstract book. Florence 2005; 374-5.
10. Verhaegen P., Borchelt M., Smith J. Relation between cardiovascular and metabolic disease and cognition in very old age: cross-sectional and longitudinal findings from the Berlin Aging Study. Health Psychol 2003; 22: 559-69.
11. Wentzel C., Rockwood K., Mac Knight C. et al. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology 2001; 57: 714-6.
Review
For citations:
Smakotina S.A., Trubnikova O.A., Barbarash O.L. Neurodynamics in young and middle-aged patients with arterial hypertension. Cardiovascular Therapy and Prevention. 2008;7(2):40-43. (In Russ.)
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