LIPID PROFILE PARAMETERS IN THE PERSONS OF YAKUT ETHNICITY WITH METABOLIC SYNDROME COMORBID WITH RESPIRATORY PATHOLOGY
https://doi.org/10.15829/1728-8800-2015-3-39-42
Abstract
Aim. To assess the parameters of lipid profile in patients with metabolic syndrome (MS) with respiratory pathology in ethnic cohort of the Yakut. Material and methods. The main group I (MG I) consisted of 88 patients of Yakut nationality with bronchial and pulmonary pathology together with metabolic syndrome. Mean age — 50,9±0,91 y. Comparison group I (CG I) was made up from 60 patients of Yakut ethnicity with lung diseases but without MS. Mean age was comparable to the one of MG I — 48,9±1,35 y. For the comparison study, depending on ethnicity we selected the II group from MG — those of Yakut ethnicity with chronic pulmonary obstructive diseases (COPD), n=39, mean age — 53,4±1,17 y. CG II consisted of 40 patients of Russian ethnicity with COPD and MS. Mean age was comparable to MG II of Yakut: 53,1±1,21 y. Lipids of blood were assessed. Results. Total cholesterol of blood (TC) in MG I was 5,5±0,13 mmol/L vs 4,7±0,17 mmol/L in CG I without MS (р=0,002); triglycerides (TG) — 1,6±0,10 mmol/L vs 1,0±0,06 mmol/L (р=0,000); low density cholesterol (LDL) — 3,5±0,09 mmol/L vs 3,0±0,12 mmol/L (р=0,007); high density cholesterol (HDL) — 1,3±0,05 mmol/L vs 1,4±0,04 (р=0,086); atherogeneity index (AI) — 4,5±0,12 vs 3,8±0,17 (р=0,004), respectively. Depending on ethnicity: TC was 5,3±0,16 mmol/L in Yakut group and 5,5±0,14 mmol/L in Russians; LDL — 3,5±0,16 mmol/L vs 3,5±0,10 mmol/L; HDL — 1,2±0,06 mmol/L vs 1,2±0,05 mmol/L, TG — 1,5±0,16 mmol/L vs 2,1±0,12 mmol/L (р=0,000), respectively. Conclusion. Lipid profile in Yakut ethnicity with COPD and MS has more negative kind in relation to TC, LDL, AI, comparing to the Yakut with the same pathology without MS. Atherogenic dyslipidemia in patients with MS and COPD irrelevant to ethnicity shows higher levels of TC, LDL in both ethnicities and hypertriglyceridemia in Russians.
About the Authors
E. P. Borisova
FSAEI HPE "North-Eastern Federal University n.a. M. K. Ammosov". Yakutsk, Russia
Russian Federation
Russian Federation
E. S. Kylbanova
FSAEI HPE "North-Eastern Federal University n.a. M. K. Ammosov". Yakutsk, Russia
Russian Federation
Russian Federation
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Review
For citations:
Borisova E.P., Kylbanova E.S. LIPID PROFILE PARAMETERS IN THE PERSONS OF YAKUT ETHNICITY WITH METABOLIC SYNDROME COMORBID WITH RESPIRATORY PATHOLOGY. Cardiovascular Therapy and Prevention. 2015;14(3):39-42. (In Russ.) https://doi.org/10.15829/1728-8800-2015-3-39-42
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