Heart rate-reducing agents ivabradine and beta-adrenoblockers in the management of patients with stable effort angina
Abstract
Coronary heart disease (CHD) is the leading lethality cause in internal medicine. Up to 38% of the patients with coronary events die within the first year. Beta-adrenoblocker (BAB) therapy does not always provide adequate heart rate (HR) reduction. To reduce HR more effectively and, therefore, to increase anti-anginal effect, BAB could be combined with an If channel inhibitor (ivabradine). Effectiveness and safety of the ivabradine + BAB combination was studied in patients with effort angina. One clinical case is presented in detail.
About the Authors
Z. M. Galeeva
Kazan State Medical Academy
Russian Federation
Kazan
Russian Federation
Kazan
N. A. Andreichev
Kazan State Medical Academy
Russian Federation
Kazan
Russian Federation
Kazan
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Review
For citations:
Galeeva Z.M., Andreichev N.A. Heart rate-reducing agents ivabradine and beta-adrenoblockers in the management of patients with stable effort angina. Cardiovascular Therapy and Prevention. 2011;10(1):59-65. (In Russ.)
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