Clinical role of increased apolipoprotein B levels in coronary heart disease
Abstract
Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD).
Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by anamnesis data, stress tests and coronary angiography results. Apo B concentration was measured by immune-enzyme method.
Results. In women, sensitivity of elevated apo B levels was lower than that of hypercholesterolemia (HCH); nevertheless, specificity of both parameters was similar. In men, HCH was more sensitive and specific than increased apo B levels.
Conclusion. Substantial differences in sensitivity and specificity of increased apo B levels were observed in women and men with possible CHD, as well as in various groups of men.
About the Authors
S. A. Pataraya
Educational and Research Medical Center, RF President Administration, Moscow
Russian Federation
Russian Federation
D. V. Preobrazhensky
Educational and Research Medical Center, RF President Administration, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Pataraya S.A., Preobrazhensky D.V. Clinical role of increased apolipoprotein B levels in coronary heart disease. Cardiovascular Therapy and Prevention. 2007;7(7):51-54. (In Russ.)
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