Uric acid – the key component of “cardio-reno-metabolic continuum”
Abstract
The recently emerged concept of cardio-reno-metabolic continuum supports common pathogenesis, development and progression risk factors (RF) for renal dysfunction and cardiovascular disease (CVD), as well as the importance of renal dysfunction, from subclinical disturbances to terminal renal failure, for CVD outcomes. Fhe review summarizes the data on uric acid as a marker of renal dysfunction and CVD RF. Original results, obtained by the authors, are also presented.
About the Authors
Zh. D. Kobalava
Russian University of People’s Friendship
Russian Federation
Russian Federation
Yu. V. Kotovskaya
Russian University of People’s Friendship
Russian Federation
Russian Federation
V. V. Tolkacheva
Russian University of People’s Friendship
Russian Federation
Russian Federation
A. S. Milto
Moscow City Clinical Hospital No. 64. Moscow
Russian Federation
Russian Federation
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Review
For citations:
Kobalava Zh.D., Kotovskaya Yu.V., Tolkacheva V.V., Milto A.S. Uric acid – the key component of “cardio-reno-metabolic continuum”. Cardiovascular Therapy and Prevention. 2008;7(4):95-100. (In Russ.)
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