Preview

Cardiovascular Therapy and Prevention

Advanced search

Reducing high risk of cardiovascular events in Type 2 diabetes mellitus: DIALOG Study results

Abstract

Aim. To study the real-world pharmaceutical reduction of high cardiovascular disease (CVD) risk in patients with Type 2 diabetes mellitus (DM-2).

Material and methods. In total, 200 DM-2 patients agreed to participate in the study, including survey, anthropometry, and laboratory tests.

Results. In two-thirds of the patients, carbohydrate metabolism was decompensated due to inadequate disease awareness, inadequate or absent glycemia self-control, and rare prescription of combined therapy. The main reasons for not achieving target blood pressure (BP) levels included high rates of monotherapy, low doses of antihypertensive drugs, inadequate treatment compliance, and low rates of BP self-control. Statins were taken by 23% of the patients, and aspirin medications – by 16%.

Conclusion. In real-world clinical settings, a substantial proportion of DM-2 patients require intensified treatment, in accordance with the concept of multi-factorial risk reduction.

About the Authors

I. E. Sapozhnikova
Kirov State Medical Academy
Russian Federation
Kirov


E. I. Tarlovskaya
Kirov State Medical Academy
Russian Federation
Kirov


A. A. Sobolev
Kirov Region Endocrinology Dispanser
Russian Federation
Kirov


E. V. Rodygina
Kirov Region Endocrinology Dispanser
Russian Federation
Kirov


References

1. Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimated for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047-53.

2. Дедов И.И., Шестакова М.В. Сахарный диабет. Москва: изд-во “Универсум Паблишинг” 2003; 282 с.

3. Johnstone MT, Nesto R, Kahn RC, et al. Joslin’s Diabetes Mellitus. Lippincott Williams & Wilkins 2004; 976-7.

4. Guadelines on diabetes, prediabetes, and cardiovascular diseases: full text. Eur Heart J Suppl 2007; 9: С3-74.

5. Сунцов Ю.И., Дедов И.И., Шестакова М.В. Скрининг осложнений сахарного диабета как метод оценки качества лечебной помощи больным. Москва 2008; 63 с.

6. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998; 317: 703-13.


Review

For citations:


Sapozhnikova I.E., Tarlovskaya E.I., Sobolev A.A., Rodygina E.V. Reducing high risk of cardiovascular events in Type 2 diabetes mellitus: DIALOG Study results. Cardiovascular Therapy and Prevention. 2009;8(7):91-94. (In Russ.)

Views: 457


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)