Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
https://doi.org/10.15829/1728-8800-2012-2-76-84
Abstract
Cardiovascular risk (CVR) stratification plays an important role in the primary prevention of atherosclerosis and associated disorders. The standard scales for CVR assessment (Framingham scale, SCORE scale, etc.) are focused on a limited number of traditional risk factors (RFs) and, therefore, neither produce precise individual risk estimates, nor increase the effectiveness of preventive interventions. One of the methods for CVR assessment optimisation is the diagnostics of subclinical atherosclerosis, based on the direct visualisation of preclinical atherosclerotic changes in arterial wall. Extracranial carotid artery (CA) ultrasound and assessment of the intima-media thickness (IMT) index or atherosclerotic plaque volume (PV) is an important method of the preclinical atherosclerosis diagnostics. The review discusses pathogenetic mechanisms of IMT increase, the standards of ultrasound IMT assessment and its interpretation, and the role of the information obtained for optimization of the CVR evaluation.
About the Authors
N. O. Katamadze
St. Petersburg Medical Academy of Post-Diploma Education, St. Petersburg
Russian Federation
Russian Federation
L. L. Berstein
St. Petersburg Medical Academy of Post-Diploma Education, St. Petersburg
Russian Federation
Russian Federation
Yu. N. Grishkin
St. Petersburg Medical Academy of Post-Diploma Education, St. Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Katamadze N.O., Berstein L.L., Grishkin Yu.N. Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification. Cardiovascular Therapy and Prevention. 2012;11(2):76-84. (In Russ.) https://doi.org/10.15829/1728-8800-2012-2-76-84
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