SURVIVAL OF THE COHORTS OF CARDIAC PATIENTS AND HEALTHY MEN AGED 40–59 YEARS: THE 30-YEAR FOLLOW-UP DATA
https://doi.org/10.15829/1728-8800-2013-2-74-79
Abstract
Aim. To assess and compare the survival in four cohorts of 40–59-yearold male residents of the South Ural Region, followed up for 30 years.
Material and methods. The four representative samples of 40–59-year-old men residing in the Metallurgichesky district, Chelyabinsk City, were defined: healthy people (H; n=174); patients with essential arterial hypertension (AH; n=149); patients with isolated myocardial infarction (MI; n=198); and patients with both MI and AH (MIAH; n=154). Over the 30-year period of prospective follow-up, the end-point was death from all causes.
Results. In H, AH, MI, and MIAH cohorts, aged at baseline 40–59 years, the cumulative 30-year survival was 24,4%, 28,2%, 7,8%, and 19,5%, respectively. There was no significant difference in the survival rates between H and AH, or MI and MIAH cohorts. At the same time, the survival rates were significantly different in the H vs. MI, H vs. MIAH, AH vs. MI, and AH vs. MIAH cohorts. The point estimates of mean and median survival time were significantly different between H and AH vs. MI and MIAH cohorts, but not for H vs. AH, or MI vs. MIAH cohorts.
Conclusion. Among 40–59-year-old men, the 30-year survival rates were significantly and negatively affected by MI. However, the survival rates were similar in MIAH and MI cohorts. Essential AH did not markedly affect the cumulative 30-year survival, compared to the H cohort. The data obtained provide annual survival estimates for the 30-year follow-up period among men aged 40–59 years, including healthy individuals and patients with AH and/or MI.
About the Authors
V. V. Belov
Chelyabinsk State Medical Academy
Russian Federation
Russian Federation
A. A. Menshchikov
South Ural State University (National Research Institute), Chelyabinsk
Russian Federation
Russian Federation
References
1. Puska P. The North Karelia Project: from community intervention to national activity in lowering cholesterol levels and CHD risk. Eur Heart J 1999;1 (Suppl.): 9–13.
2. Shalnova SA, Deev AD, Vilkov VG, et al. Individual prediction of the likelihood of death from the data of a study of risk factors and load testing in ablebodied males. Preventive maintenance of diseases and health strengthening 2005; 4: 18–22. Russian (Шальнова С. А., Деев А. Д., Вилков В. Г. и др. Индивидуальный прогноз вероятности смерти по данным исследования факторов риска и нагрузочного тестирования у мужчин трудоспособного возраста. Профил забол укреп здоровья 2005; 4: 18–22).
3. Fletcher RH, Fletcher SW, Wagner EH. Clinical Epidemiology. Bases of demonstrative medicine. Moscow: Media Sfera 1998; 345p. Russian (Флетчер Ф., Флетчер С., Вагнер Э. Клиническая эпидемиология. Основы доказательной медицины. Пер. c англ. Москва: Медиа Сфера 1998; 345 с).
4. The instruction on prophylactic medical examination of the patients almost healthy, and persons with risk factors in out-patient-polyclinic establishments (divisions). Moscow; 1986. 155p. Russian (Инструкция по диспансеризации больных, практически здоровых, и лиц с факторами риска в амбулаторнополиклинических учреждениях (подразделениях). Москва 1986; 155 с).
5. Hill AB. Bases of medical statistics. Moscow: Medgiz; 1958.306 p. Russian (Хилл А. Б. Основы медицинской статистики. Пер. с англ. Москва: Медгиз 1958; 306 с).
6. Rose GA, Blackburn H, Gillim RF, et al. Cardiovascular Survey Methods. 2th ed. Geneva, WHO 1984. 223 p. (Роуз Дж., Блэкберн Г., Гиллум Р. Ф. и др. Эпидемиологические методы изучения сердечно-сосудистых заболева- ний. Женева: ВОЗ 1984; 223 с).
7. Myocardial Infarction Community Registers. Geneva, WHO 1976. 123 p.
8. Lang N, Secic V. How To Report Statistics in Medicine. Annotated Guidelines for Authors, Editors, and Reviewers. Moscow: Prakticheskajamedicina 2011; 480 p. Russian (Ланг Т. А., Сесик М. Как описывать статистику в медицине. Аннотированное руководство для авторов, редакторов и рецензентов. Пер. с англ. Москва: Практическая медицина 2011; 480 с).
9. Vlasov VV. Epidemiologija: the manual for high schools. Moscow: GOJeTAR; 2004; 464 p. Russian (Власов В. В. Эпидемиология: учебное пособие для вузов. Москва: ГОЭТАР 2004; 464 с).
10. The complex report on a condition of a surrounding environment of the Chelyabinsk area in 2002. Chelyabinsk 2002; 8. Russian (Комплексный доклад о состоянии окружающей природной среды Челябинской области в 2002 году. Челябинск 2002; 8).
11. Gudmundsson LS, Johannsson M, Thorgeirsson G, et al. Cardiovasc Hypertension control as predictor of mortality in treated men and women, followed for up to 30 years. Drugs Ther 2005; 19 (3):227–35.
12. Almgren T, Persson B, Wilhelmsen L, et al. Stroke and coronary heart disease in treated hypertension — a prospective cohort study over three decades. J Intern Med 2005; 257 (6): 496–502.
13. Salminen M, Kuoppamäki M, Vahlberg T, et al. The metabolic syndrome defined by modified International Diabetes Federation criteria and mortality: a 9-year follow-up of the aged in Finland. Diabets Metab 2010; 36 (6): 437–42.
14. Rodriquez DL, Lau N, Burchfiell CM. Glucose intolerance and 23-year risk of coronary heart disease and total mortality: the Honolules Heart Program. Diabets-Care 1999; 23 (8): 1262–5.
15. Menshikow AA. Dependence between risk factors ИБС, cardiovascular diseases, changes of plasma fibers and death rate among men of 40–59 years (according to 10-year-old prospective study): The dissertation author’s abstract on competition of degree of the candidate of medical sciences. Chelyabinsk 2002. Russian (Меньщиков А. А. Зависимость между факторами риска ИБС, сердечно- сосудистыми заболеваниями, изменениями плазменных белков и смер- тностью среди мужчин 40–59 лет (по данным 10-летнего проспективного наблюдения): Автореф дис канд мед наук. Челябинск 2002).
16. Preobrazhenskij DV. Hypercholesterinemia at men and women of various age. A part II. An efficiency and safety problem statins. Kardiologija 2007; 11: 75–85. Russian (Преображенский Д. В. Гиперхолестеринемия у мужчин и женщин различного возраста. Часть II. Проблема эффективности и безопасности статинов. Кардиология 2007; 11: 75–85).
Review
For citations:
Belov V.V., Menshchikov A.A. SURVIVAL OF THE COHORTS OF CARDIAC PATIENTS AND HEALTHY MEN AGED 40–59 YEARS: THE 30-YEAR FOLLOW-UP DATA. Cardiovascular Therapy and Prevention. 2013;12(2):74-79. (In Russ.) https://doi.org/10.15829/1728-8800-2013-2-74-79
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