Clinical role of the “symptom-balloon” time in endovascular treatment of acute coronary syndrome with ST segment elevation
Abstract
Aim. To investigate the clinical effectiveness of endovascular revascularization of the infarct-related coronary artery (IRCA) in regard to the “symptom-balloon” time, analyzing retrospective data on patients with acute coronary syndrome (ACS) and ST segment elevation (STE-ACS).
Material and methods. The study included 164 patients with STE-ACS, who underwent selective coronary angiography (CAG) and transluminal balloon angioplasty (TLBAP) with coronary stenting. Based on the “symptom-balloon” time, all patients were divided into two groups. In Group I (n=78), the “symptom-balloon” time was <6 hours, while in Group II (n=86), it was 6–24 hours. Echocardiography (EchoCG) was performed at Day 1, 7, and 30.
Results. The EchoCG data demonstrated a reduction in left ventricular (LV) systolic function. In Group I, LV systolic function significantly improved by Day 7: LV ejection fraction (EF) increased from 48,2% to 51,6% (p=0,0013). At Day 30, LV EF was 54,7% (p=0,001). In Group II, the increase in LV EF was not statistically significant (from 46,1% to 47,2%; p=0,2197).
Conclusion. Urgent coronary revascularization in STE-ACS improved localLV contractility, due to the restriction of stunned myocardium areas. The speed of theLV contractility improvement after IRCA TLBAP/coronary stenting was strongly associated with the “symptom-balloon” time.
About the Authors
A. L. Alyavi
Republican Centre for Emergency Healthcare
Uzbekistan
Tashkent
Uzbekistan
Tashkent
Kh. Kh. Madzhitov
Republican Centre for Emergency Healthcare
Uzbekistan
Tashkent
Uzbekistan
Tashkent
D. A. Alimov
Republican Centre for Emergency Healthcare
Uzbekistan
Tashkent
Uzbekistan
Tashkent
M. K. Kenzhaev
Republican Centre for Emergency Healthcare
Uzbekistan
Tashkent
Uzbekistan
Tashkent
Zh. Zh. Payziev
Republican Centre for Emergency Healthcare
Uzbekistan
Tashkent
Uzbekistan
Tashkent
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Review
For citations:
Alyavi A.L., Madzhitov Kh.Kh., Alimov D.A., Kenzhaev M.K., Payziev Zh.Zh. Clinical role of the “symptom-balloon” time in endovascular treatment of acute coronary syndrome with ST segment elevation. Cardiovascular Therapy and Prevention. 2011;10(8):52-56. (In Russ.)
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