A clinical case of radiofrequency pulmonary artery denervation for treatment of a patient with residual chronic thromboembolic pulmonary hypertension
D. A. Feshchenko,
B. A. Rudenko,
O. M. Drapkina,
N. E. Gavrilova,
A. S. Shanoyan,
F. B. Shukurov,
D. K. Vasiliev https://doi.org/10.15829/1728-8800-2019-6-121-125
Abstract
Improving the methods of diagnosis, therapy and surgical treatment of chronic thromboembolic pulmonary hypertension (CTEPH) provides a complete cure in most cases. Data on the survival of CTELH patients is contradictory, and primarily due to the treatment availability. In Russian Federation there are few experienced centers performing thromboendarterectomy and balloon pulmonary angioplasty. Until recently, specific drug therapy was not available for most patients because of its high cost. The presented clinical case demonstrates modern opportunities of treatment of inoperable patients with residual CTEPH by the method of pulmonary artery denervation using a radiofrequency ablation.
About the Authors
D. A. Feshchenko
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
B. A. Rudenko
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
O. M. Drapkina
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
N. E. Gavrilova
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
A. S. Shanoyan
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
F. B. Shukurov
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
D. K. Vasiliev
National Medical Research Center for Preventive Medicine
Russian Federation
Russian Federation
Moscow.
References
1. Galie N, Hoeper M, Humbert M, et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology and of the European Respiratory Society. Eur Heart J. 2016;37:67-119. doi:10.1093/eurheartj/ehv317.
2. Lang IM, Mayer E, Simonneau G, Rubin LJ. Chronic thromboembolic pulmonary hypertension. Circulaion. 2006;113:2011-20. doi:10.1161/CIRCULATIONAHA.105.602565.
3. Bonderman D, Wilkens H, Wakounig S, et al. Risk factors for chronic thromboembolic pulmonary hypertension. Eur Respir J. 2009;33:325-31. doi:10.1183/09031936.00087608.
4. Condliffe R, Kiely DG, Gibbs JS, Corris PA, et al. Improved outcomes in medically and surgically treated chronic thromboembolic pulmonary hypertension. Am J Respir Crit Care Med. 2008;177:1122-7. doi:10.1164/rccm.200712-1841OC.
5. Bhama-Ariza P, Keogh AM, Muller DW. Percutaneus interventional therapies for the treatment of patients with severe pulmonary hypertension. JACC. 2014;63:611-8. doi:10.1016/j.jacc.2013.11.022.
6. Verity MA, Bevan JA. Fine structural study of the terminal effector plexus, neuromuscular and intermuscular relationships in the pulmonary artery. J Anat. 1968;103(1):49-63.
7. Richardson JB. Nerve supply to the lungs. Am Rev Respir Dis. 1979;119(5):785-802.
8. Chen SL, Zhang YJ, Zhou L, et al. Percutaneous pulmonary artery denervation completely abolishes experimental pulmonary arterial hypertension in vivo. EuroIntervention. 2013;9(2):269-76. doi:10.4244/EIJV9I2A43.
9. Chen SL, Zhang H, Xie DJ, et al. Hemodynamic, functional, and clinical responses to pulmonary artery denervation in patients with pulmonary arterial hypertension of different causes: phase II results from the Pulmonary Artery Denervation-1 Study. Circ Cardiovasc Interv. 2015;8:e002837. doi:10.1161/CIRCINTERVENTIONS.115.002837.
Review
For citations:
Feshchenko D.A., Rudenko B.A., Drapkina O.M., Gavrilova N.E., Shanoyan A.S., Shukurov F.B., Vasiliev D.K. A clinical case of radiofrequency pulmonary artery denervation for treatment of a patient with residual chronic thromboembolic pulmonary hypertension. Cardiovascular Therapy and Prevention. 2019;18(6):121-125. (In Russ.) https://doi.org/10.15829/1728-8800-2019-6-121-125
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