The effectiveness of catheter ablation in paroxysmal atrial fibrillation in patients with obstructive sleep apnea with/without use of continuous positive airway pressure: results of a 12-month follow-up
https://doi.org/10.15829/1728-8800-2020-2427
Abstract
Aim. To assess the effectiveness of catheter ablation in paroxysmal atrial fibrillation (AF) in patients with moderate/severe obstructive sleep apnea (OSA) with/without use of continuous positive airway pressure (CPAP) therapy (>4 hours per night).
Material and methods. A total of 60 patients with paroxysmal AF and moderate/severe OSA after catheter pulmonary vein isolation were randomized into 2 groups (2:1 ratio): CPAP group (n=40) and control group (n=20). The follow-up period was 12 months and included visits after 3, 6 and 12 months. The effectiveness of catheter ablation was assessed after the 3-month blind period.
Results. Freedom from arrhythmia in patients with CPAP therapy was documented in 82,9% and was significantly more common compared with the control group — 47,5% (p=0,032). Concurrent hypertension was a predictor of arrhythmia recurrence (odds ratio 24,1; 95% confidence interval 2,2-261,2).
Conclusion. Treatment of OSA with CPAP therapy improves the effectiveness of catheter ablation in paroxysmal AF during a 12-month follow-up.
About the Authors
K. V. Davtyan
Национальный медицинский исследовательский центр профилактической медицины Минздрава России
Russian Federation
Russian Federation
G. G. Arutyunyan
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Moscow
Russian Federation
Moscow
A. G. Topchyan
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Moscow
Russian Federation
Moscow
O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Davtyan K.V., Arutyunyan G.G., Topchyan A.G., Drapkina O.M. The effectiveness of catheter ablation in paroxysmal atrial fibrillation in patients with obstructive sleep apnea with/without use of continuous positive airway pressure: results of a 12-month follow-up. Cardiovascular Therapy and Prevention. 2020;19(2):2427. (In Russ.) https://doi.org/10.15829/1728-8800-2020-2427
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