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COMORBIDITIES OF ISCHEMIC HEART DISEASE WITH OTHER NON-COMMUNICABLE DISEASES IN ADULT POPULATION: AGE AND RISK FACTORS ASSOCIATION

https://doi.org/10.15829/1728-8800-2015-4-44-51

Abstract

Aim. To study the prevalence of ischemic heart disease as one of the most common cardiovascular disorders, together with arterial hypertension (AH), diabetes mellitus (DM) and liver diseases (LD) in adult (25-64 y.o.) population of selected RF regions, the variance of those with gender and age, and association of cardiovascular risk factors (FR).

Material and methods. Into analysis we included the results of representative selections studies from 13 RF regions, studied according to the program of multicenter study ESSE-RF during the years 2012­2014; totally 21923 patients studied. Investigation included standard questioning, including anamnesis. For statistics we used applied software SAS.

Results. In men the prevalence of IHD is associated with the growth of comorbidity from 0 in the age group 25-34 y. to 77% in the age 55-64 y., almost duplicating every decade. For women there is analogic tendency, less prominent. In men there are significant associations only with AH, which increases the risk of IHD 2,5 times, though in women together with AH the associations are significant for LD. Comorbidities with DM do not influence the prevalence of IHD in men and women. At the same time, any association with two diseases increases the risk of IHD >304 times. The most negative is the association of all three diseases, with which IHD is 8,7 times more prevalent, than in their absence. Using multidimensional logistic regression after correction for the age and comorbidity in the patients with IHD of both genders, there are associations revealed of high density cholesterol lipoproteids (HDL) in blood and abdominal obesity. In men there are also positive associations with smoking and negative — with increased cholesterol.

Conclusion. Comorbidities of IHD with AH, DM and LD in adult population are common, are associated with the general FR, are increasing with the age. Taking modern tendencies of population ageing, it is plausible to expect an increase of the prevalence of comorbidities, that requires a necessity of the healthcare services to these changes.

 

About the Authors

S. A. Shalnova
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


R. G. Oganov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


A. D. Deev
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


A. E. Imaeva
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


М. М. Lukyanov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


G. V. Artamonova
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS. Kemerovo, Russia
Russian Federation


Т. М. Gatagonova
SEI HPE "North-Osetin State Medical Academy". Vladicaucaz, Northern Osetia-Alania, Russia
Russian Federation


Yu. I. Grinshtein
SBEI HPE "Krasnoyarsk State Medical University n.a. Voyno-Yasenetsky" of the Healthcare Ministry. Krasnoyarsk, Russia
Russian Federation


D. V. Duplyakov
SBHI "Samara Region Clinical Cardiological Dispensary". Samara, Russia
Russian Federation


А. Yu. Efanov
SBEI HPE "Tyumen State Medical Academy" of the Healthcare Ministry. Tyumen, Russia
Russian Federation


Yu. V. Zhernakova
FSBI "Russian Cardiovascular Scientific-Production Complex" of the Healthcare Ministry. Moscow, Russia
Russian Federation


V. A. Ilyin
FSSI "Institute of Social and Economic Territories Development" RAS. Vologda, Russia
Russian Federation


R. A. Libis
SBEI HPE "Orenburg State Medical Academy" of the Healthcare Ministry. Orenburg, Russia
Russian Federation


A. V. Minakov
SBEI HPE "Voronezh State Medical Academy" of the Healthcare Ministry. Voronezh, Russia
Russian Federation


V. A. Nevzorova
SBEI HPE "Pacific-Ocean State Medical University" of the Healthcare Ministry. Vladivostok, Russia
Russian Federation


S. V. Nedogoda
SBEI HPE "Volgograd State Medical University" of the Healthcare Ministry. Volgograd, Russia
Russian Federation


S. A. Romanchuk
DBHI "Cardiovascular Dispensary". Ivanovo, Russia
Russian Federation


O. P. Rotar
FSBI "Almazov North-Western Federal Medical Research Center" of the Healthcare Ministry. Saint-Petersburg, Russia
Russian Federation


I. A. Trubacheva
FSBSI "Scientific-Research Institute of Cardiology". Tomsk, Russia
Russian Federation


E. V. Shlyakhto
FSBI "Almazov North-Western Federal Medical Research Center" of the Healthcare Ministry. Saint-Petersburg, Russia
Russian Federation


S. A. Boytsov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


Yu. A. Balanova
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


G. A. Muromtseva
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


S. E. Evstifeeva
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


A. V. Kapustina
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


M. N. Mamedov
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


S. K. Gutnova
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


Z. A. Toguzova
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


G. V. Tolparov
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


N. V. Kulakova
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


N. V. Shestakova
Всесоюз. кардиол. науч. центр АМН СС. Ин-т клин. кардиологии им. А. Л. Мясникова
Russian Federation


M. V. Mokshina
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


L. V. Rodionova
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


E. V. Chumachek
DBHI “Cardiovascular Dispensary”
Russian Federation


A. A. Ledyaeva
DBHI “Cardiovascular Dispensary”
Russian Federation


R. A. Kasimov
Ярославский государственный педагогический университет им. К.Д. Ушинского
Russian Federation


A. A. Shabunova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


G. V. Leonidova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


K. N. Kalashnikov
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


O. N. Kalachikova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


A. I. Rossoshansky
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


N. A. Kondakova
Вологодский научный центр РАН
Russian Federation


A. V. Popov
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


K. A. Ustinova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


G. I. Furmenko
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


N. I. Babenko
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


O. G. Azarin
ГБОУ ВПО “Воронежская государственная медицинская академия” Минздрава России
Russian Federation


L. V. Bondartsov
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


A. E. Khvostikova
ГБОУ ВПО “Воронежская государственная медицинская академия” Минздрава России
Russian Federation


O. A. Nazarova
FSBI “Almazov North-Western Federal Medical Research Center” of the Healthcare Ministry
Russian Federation


O. A. Belova
ОБУЗ “Кардиологический диспансер”
Russian Federation


E. A. Shutemova
FSBI “Almazov North-Western Federal Medical Research Center” of the Healthcare Ministry


M. M. Petrova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


L. K. Danilova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. A. Evsyukov
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


N. V. Topolskaya



V. V. Shabalin
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. I. Aristov
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


R. R. Ruf
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. A. Kosinova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


E. N. Shmatova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


D. S. Kaskaeva
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


I. R. Basyrova
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


V. Yu. Kondratenko

Russian Federation


E. A. Lopina
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


D. V. Safonova
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


S. A. Gudkova
Российский научный центр хирургии им. акад. Б.В. Петровского
Russian Federation


N. A. Cherepanova
SBHI “Samara Region Clinical Cardiological Dispensary”
Russian Federation


R. S. Karpov
Томский национальный исследовательский медицинский центр Российской академии наук, Научно-исследовательский институт кардиологии
Russian Federation


V. S. Kaveshnikov
Томский национальный исследовательский медицинский центр Российской академии наук
Russian Federation


V. N. Serebryakova
Томский национальный исследовательский медицинский центр Российской академии наук
Russian Federation


I. V. Medvedeva
SBEI HPE “Tyumen State Medical Academy” of the Healthcare Ministry
Russian Federation


V. P. Shava
Тюменский отдел Южно-Уральского НЦ РАМН
Russian Federation


S. V. Shalaev
SBEI HPE “Tyumen State Medical Academy” of the Healthcare Ministry
Russian Federation


O. L. Barbarash
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


A. E. Skripchenko
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


E. V. Indukaeva
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


T. A. Mulerova
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


S. A. Maksimov
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


N. V. Cherkass
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


M. V. Tabakaev
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


Ya. V. Danilchenko
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


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Review

For citations:

Shalnova S.A., Oganov R.G., Deev A.D., Imaeva A.E., Lukyanov М.М., Artamonova G.V., Gatagonova Т.М., Grinshtein Yu.I., Duplyakov D.V., Efanov А.Yu., Zhernakova Yu.V., Ilyin V.A., Libis R.A., Minakov A.V., Nevzorova V.A., Nedogoda S.V., Romanchuk S.A., Rotar O.P., Trubacheva I.A., Shlyakhto E.V., Boytsov S.A., Balanova Yu.A., Muromtseva G.A., Evstifeeva S.E., Kapustina A.V., Mamedov M.N., Gutnova S.K., Toguzova Z.A., Tolparov G.V., Kulakova N.V., Shestakova N.V., Mokshina M.V., Rodionova L.V., Chumachek E.V., Ledyaeva A.A., Kasimov R.A., Shabunova A.A., Leonidova G.V., Kalashnikov K.N., Kalachikova O.N., Rossoshansky A.I., Kondakova N.A., Popov A.V., Ustinova K.A., Furmenko G.I., Babenko N.I., Azarin O.G., Bondartsov L.V., Khvostikova A.E., Nazarova O.A., Belova O.A., Shutemova E.A., Petrova M.M., Danilova L.K., Evsyukov A.A., Topolskaya N.V., Shabalin V.V., Aristov A.I., Ruf R.R., Kosinova A.A., Shmatova E.N., Kaskaeva D.S., Basyrova I.R., Kondratenko V.Yu., Lopina E.A., Safonova D.V., Gudkova S.A., Cherepanova N.A., Karpov R.S., Kaveshnikov V.S., Serebryakova V.N., Medvedeva I.V., Shava V.P., Shalaev S.V., Barbarash O.L., Skripchenko A.E., Indukaeva E.V., Mulerova T.A., Maksimov S.A., Cherkass N.V., Tabakaev M.V., Danilchenko Ya.V. COMORBIDITIES OF ISCHEMIC HEART DISEASE WITH OTHER NON-COMMUNICABLE DISEASES IN ADULT POPULATION: AGE AND RISK FACTORS ASSOCIATION. Cardiovascular Therapy and Prevention. 2015;14(4):44-51. (In Russ.) https://doi.org/10.15829/1728-8800-2015-4-44-51

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