Preview

User

Not a user? Register with this site Forgot your password?

Cardiovascular Therapy and Prevention

Advanced search

COMORBIDITIES OF ISCHEMIC HEART DISEASE WITH OTHER NON-COMMUNICABLE DISEASES IN ADULT POPULATION: AGE AND RISK FACTORS ASSOCIATION

https://doi.org/10.15829/1728-8800-2015-4-44-51

Abstract

Aim. To study the prevalence of ischemic heart disease as one of the most common cardiovascular disorders, together with arterial hypertension (AH), diabetes mellitus (DM) and liver diseases (LD) in adult (25-64 y.o.) population of selected RF regions, the variance of those with gender and age, and association of cardiovascular risk factors (FR).

Material and methods. Into analysis we included the results of representative selections studies from 13 RF regions, studied according to the program of multicenter study ESSE-RF during the years 2012­2014; totally 21923 patients studied. Investigation included standard questioning, including anamnesis. For statistics we used applied software SAS.

Results. In men the prevalence of IHD is associated with the growth of comorbidity from 0 in the age group 25-34 y. to 77% in the age 55-64 y., almost duplicating every decade. For women there is analogic tendency, less prominent. In men there are significant associations only with AH, which increases the risk of IHD 2,5 times, though in women together with AH the associations are significant for LD. Comorbidities with DM do not influence the prevalence of IHD in men and women. At the same time, any association with two diseases increases the risk of IHD >304 times. The most negative is the association of all three diseases, with which IHD is 8,7 times more prevalent, than in their absence. Using multidimensional logistic regression after correction for the age and comorbidity in the patients with IHD of both genders, there are associations revealed of high density cholesterol lipoproteids (HDL) in blood and abdominal obesity. In men there are also positive associations with smoking and negative — with increased cholesterol.

Conclusion. Comorbidities of IHD with AH, DM and LD in adult population are common, are associated with the general FR, are increasing with the age. Taking modern tendencies of population ageing, it is plausible to expect an increase of the prevalence of comorbidities, that requires a necessity of the healthcare services to these changes.

 

About the Authors

S. A. Shalnova
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


R. G. Oganov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


A. D. Deev
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


A. E. Imaeva
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


М. М. Lukyanov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


G. V. Artamonova
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS. Kemerovo, Russia
Russian Federation


Т. М. Gatagonova
SEI HPE "North-Osetin State Medical Academy". Vladicaucaz, Northern Osetia-Alania, Russia
Russian Federation


Yu. I. Grinshtein
SBEI HPE "Krasnoyarsk State Medical University n.a. Voyno-Yasenetsky" of the Healthcare Ministry. Krasnoyarsk, Russia
Russian Federation


D. V. Duplyakov
SBHI "Samara Region Clinical Cardiological Dispensary". Samara, Russia
Russian Federation


А. Yu. Efanov
SBEI HPE "Tyumen State Medical Academy" of the Healthcare Ministry. Tyumen, Russia
Russian Federation


Yu. V. Zhernakova
FSBI "Russian Cardiovascular Scientific-Production Complex" of the Healthcare Ministry. Moscow, Russia
Russian Federation


V. A. Ilyin
FSSI "Institute of Social and Economic Territories Development" RAS. Vologda, Russia
Russian Federation


R. A. Libis
SBEI HPE "Orenburg State Medical Academy" of the Healthcare Ministry. Orenburg, Russia
Russian Federation


A. V. Minakov
SBEI HPE "Voronezh State Medical Academy" of the Healthcare Ministry. Voronezh, Russia
Russian Federation


V. A. Nevzorova
SBEI HPE "Pacific-Ocean State Medical University" of the Healthcare Ministry. Vladivostok, Russia
Russian Federation


S. V. Nedogoda
SBEI HPE "Volgograd State Medical University" of the Healthcare Ministry. Volgograd, Russia
Russian Federation


S. A. Romanchuk
DBHI "Cardiovascular Dispensary". Ivanovo, Russia
Russian Federation


O. P. Rotar
FSBI "Almazov North-Western Federal Medical Research Center" of the Healthcare Ministry. Saint-Petersburg, Russia
Russian Federation


I. A. Trubacheva
FSBSI "Scientific-Research Institute of Cardiology". Tomsk, Russia
Russian Federation


E. V. Shlyakhto
FSBI "Almazov North-Western Federal Medical Research Center" of the Healthcare Ministry. Saint-Petersburg, Russia
Russian Federation


S. A. Boytsov
FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia
Russian Federation


Yu. A. Balanova
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


G. A. Muromtseva
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


S. E. Evstifeeva
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


A. V. Kapustina
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


M. N. Mamedov
FSBI “State Scientific-Prevention Center of the Prevention Medicine” of the Healthcare Ministry
Russian Federation


S. K. Gutnova
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


Z. A. Toguzova
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


G. V. Tolparov
SEI HPE “North-Osetin State Medical Academy”
Russian Federation


N. V. Kulakova
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


N. V. Shestakova
Всесоюз. кардиол. науч. центр АМН СС. Ин-т клин. кардиологии им. А. Л. Мясникова
Russian Federation


M. V. Mokshina
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


L. V. Rodionova
ГБОУ ВПО “Тихоокеанский государственный медицинский университет” Минздрава России
Russian Federation


E. V. Chumachek
DBHI “Cardiovascular Dispensary”
Russian Federation


A. A. Ledyaeva
DBHI “Cardiovascular Dispensary”
Russian Federation


R. A. Kasimov
Ярославский государственный педагогический университет им. К.Д. Ушинского
Russian Federation


A. A. Shabunova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


G. V. Leonidova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


K. N. Kalashnikov
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


O. N. Kalachikova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


A. I. Rossoshansky
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


N. A. Kondakova
Вологодский научный центр РАН
Russian Federation


A. V. Popov
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


K. A. Ustinova
FSSI “Institute of Social and Economic Territories Development” RAS
Russian Federation


G. I. Furmenko
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


N. I. Babenko
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


O. G. Azarin
ГБОУ ВПО “Воронежская государственная медицинская академия” Минздрава России
Russian Federation


L. V. Bondartsov
SBEI HPE “Pacific-Ocean State Medical University” of the Healthcare Ministry
Russian Federation


A. E. Khvostikova
ГБОУ ВПО “Воронежская государственная медицинская академия” Минздрава России
Russian Federation


O. A. Nazarova
FSBI “Almazov North-Western Federal Medical Research Center” of the Healthcare Ministry
Russian Federation


O. A. Belova
ОБУЗ “Кардиологический диспансер”
Russian Federation


E. A. Shutemova
FSBI “Almazov North-Western Federal Medical Research Center” of the Healthcare Ministry


M. M. Petrova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


L. K. Danilova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. A. Evsyukov
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


N. V. Topolskaya



V. V. Shabalin
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. I. Aristov
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


R. R. Ruf
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


A. A. Kosinova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


E. N. Shmatova
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


D. S. Kaskaeva
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
1, P. Zeleznyaka street, Krasnoyarsk, 660022, Krasnoyarsk


I. R. Basyrova
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


V. Yu. Kondratenko

Russian Federation


E. A. Lopina
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


D. V. Safonova
SBEI HPE “Voronezh State Medical Academy” of the Healthcare Ministry
Russian Federation


S. A. Gudkova
Российский научный центр хирургии им. акад. Б.В. Петровского
Russian Federation


N. A. Cherepanova
SBHI “Samara Region Clinical Cardiological Dispensary”
Russian Federation


R. S. Karpov
Томский национальный исследовательский медицинский центр Российской академии наук, Научно-исследовательский институт кардиологии
Russian Federation


V. S. Kaveshnikov
Томский национальный исследовательский медицинский центр Российской академии наук
Russian Federation


V. N. Serebryakova
Томский национальный исследовательский медицинский центр Российской академии наук
Russian Federation


I. V. Medvedeva
SBEI HPE “Tyumen State Medical Academy” of the Healthcare Ministry
Russian Federation


V. P. Shava
Тюменский отдел Южно-Уральского НЦ РАМН
Russian Federation


S. V. Shalaev
SBEI HPE “Tyumen State Medical Academy” of the Healthcare Ministry
Russian Federation


O. L. Barbarash
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


A. E. Skripchenko
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


E. V. Indukaeva
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


T. A. Mulerova
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


S. A. Maksimov
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


N. V. Cherkass
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


M. V. Tabakaev
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


Ya. V. Danilchenko
FSBI Scientific-Research Institute of Complex Problems of Cardiovascular Diseases SD RAMS
Russian Federation


References

1. Ford ES, Capewell S. Proportion of the decline in cardiovascular mortality disease due to prevention versus treatment: public health versus clinical care. Ann Rev Public Health 2011; 21; 32: 5-22.

2. Aspelund T, Gudnason V, Magnusdottir BT, et al. Analysing the large decline in coronary heart disease mortality in the Icelandic population aged 25-74 between the years 1981 and 2006. PLoS One 2010 12; 5(11): e13957.

3. Palmieri L, Bennett K, Giampaoli S, et al. Explaining the decrease in coronary heart disease mortality in Italy between 1980 and 2000. Am J Public Health 2010; 100(4): 684-92. Epub 2009 Jul 16.

4. Andreev EM, Kvasha EA, Har’kova TL. Life expectancy in Russia: recovery growth. http://demoscope.ru/weekly/2014/0621/tema01.php. Russian (Андреев Е. М., Кваша Е. А., Харькова Т. Л. Продолжительность жизни в России: восстановительный рост. http://demoscope.ru/weekly/2014/0621/tema01.php)

5. Salive ME. Multimorbidity in older adults. Epidemiol Rev 2013; 35: 75-83.

6. Ward BW, Schiller JS. Prevalence of multiple chronic conditions among US adults: estimates from the National Health Interview Survey, 2010. Prev Chronic Dis 2013; 10: E65.

7. Barnett K, Mercer SW, Norbury M, et al. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 2012; 380: 37-43.

8. St Sauver JL, Boyd CM, Grossardt BR, et al. Risk of developing multimorbidity across all ages in an historical cohort study: differences by sex and ethnicity. BMJ Open 2015;5: e006413. doi:10.1136/bmjopen-2014-006413.

9. AIHW: Tong B & Stevenson C 2007. Comorbidity of cardiovascular disease, diabetes and chronic kidney disease in Australia. Cardiovascular Disease Series no. 28. Cat. no. CVD 37.Canberra: AIHW.

10. Oganov RG. Vascular comorbidity: general approaches to prevention and treatment. Rational Pharmacotherapy in Cardiology; 2015; 11 (1): 4-7. Russian (Оганов Р. Г. Сосудистая коморбидность: общие подходы к профилактике и лечению. Рациональная Фармакотерапия в Кардиологии 2015; 11 (1): 4-7).

11. Targher G, Day CP, Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. New Engl J Med 2010; 363 (14): 1341-5.

12. Hamaguchi M, Kojima T, Takeda N, et al. Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World J Gastroenterol 2007; 13: 1579-84.

13. Kim NH, Park J, Kim SH, et al. Non-alcoholic fatty liver disease, metabolic syndrome and subclinical cardiovascular changes in the general population Heart 2014; 100(12): 938-43.

14. Drapkina OM, Deeva TA, Volkova NP, Ivashkin VT. Current approaches to diagnosing and treating nonalcoholic fatty liver disease. Ter Arkh 2014; 86(10):116-23. Russian (Драпкина О.М, Деева Т.А., Волкова Н.П., Ивашкин В.Т. Современные подходы к диагностике и лечению неалкогольной жировой болезни печени. Терапевтический архив 2014; 10: 116-23).

15. Scientific Organizing Committee of the ESSE-RF. Epidemiology of cardiovascular diseases in different regions of Russia (ESSE-RF). The rationale for and design of the study. Preventive Medicine 2013; 6: 25-34. Russian (Научно-организационный комитет проекта ЭССЕ-РФ. Эпидемиология сердечно-сосудистых заболеваний в различных регионах России (ЭССЕ-РФ). Обоснование и дизайн исследования. Профилактическая медицина 2013; 6: 25-34).

16. Vogeli C, Shields AE, Lee TA, et al. Multiple chronic conditions: prevalence, health consequences, and implications for quality, care management, and costs. J Gen Intern Med 2007; 22(Suppl 3): 391-5.

17. Sinnott C, Mc Hugh S, Browne J, et al. GPs’ perspectives on the management of patients with multimorbidity: systematic review and synthesis of qualitative research. BMJ Open 2013;3:e003610.

18. Drapkina OM, Ivashkin VT. Nealkogol’naja zhirovaja bolezn’ pecheni kak komponent metabolicheskogo sindroma. Ros med vesti 2010; 2: 72-9. Russian (Драпкина О. М., Ивашкин В. Т. Неалкогольная жировая болезнь печени как компонент метаболического синдрома. Рос мед вести 2010; 2: 72-9).

19. Boytsov SA, Luk’yanov MM, Yakushin SS, et al. Cardiovascular diseases registry (RECVASA): diagnostics, concomitant cardiovascular pathology, comorbidities and treatment in the real outpatient-polyclinic practice. Cardiovascular therapy and prevention. 2014; 13(6): 44–50. (Бойцов С.А., Лукьянов М.М., Якушин C.С., и соавт. Регистр кардиоваскулярных заболеваний (РЕКВАЗА): диагностика, сочетанная сердечно-сосудистая патология, сопутствующие заболевания и лечение в условиях реальной амбулаторно-поликлинической практики. Кардиоваскулярная терапия и профилактика 2014; 13(6): 44-50).


Review

For citations:

Shalnova S.A., Oganov R.G., Deev A.D., Imaeva A.E., Lukyanov М.М., Artamonova G.V., Gatagonova Т.М., Grinshtein Yu.I., Duplyakov D.V., Efanov А.Yu., Zhernakova Yu.V., Ilyin V.A., Libis R.A., Minakov A.V., Nevzorova V.A., Nedogoda S.V., Romanchuk S.A., Rotar O.P., Trubacheva I.A., Shlyakhto E.V., Boytsov S.A., Balanova Yu.A., Muromtseva G.A., Evstifeeva S.E., Kapustina A.V., Mamedov M.N., Gutnova S.K., Toguzova Z.A., Tolparov G.V., Kulakova N.V., Shestakova N.V., Mokshina M.V., Rodionova L.V., Chumachek E.V., Ledyaeva A.A., Kasimov R.A., Shabunova A.A., Leonidova G.V., Kalashnikov K.N., Kalachikova O.N., Rossoshansky A.I., Kondakova N.A., Popov A.V., Ustinova K.A., Furmenko G.I., Babenko N.I., Azarin O.G., Bondartsov L.V., Khvostikova A.E., Nazarova O.A., Belova O.A., Shutemova E.A., Petrova M.M., Danilova L.K., Evsyukov A.A., Topolskaya N.V., Shabalin V.V., Aristov A.I., Ruf R.R., Kosinova A.A., Shmatova E.N., Kaskaeva D.S., Basyrova I.R., Kondratenko V.Yu., Lopina E.A., Safonova D.V., Gudkova S.A., Cherepanova N.A., Karpov R.S., Kaveshnikov V.S., Serebryakova V.N., Medvedeva I.V., Shava V.P., Shalaev S.V., Barbarash O.L., Skripchenko A.E., Indukaeva E.V., Mulerova T.A., Maksimov S.A., Cherkass N.V., Tabakaev M.V., Danilchenko Ya.V. COMORBIDITIES OF ISCHEMIC HEART DISEASE WITH OTHER NON-COMMUNICABLE DISEASES IN ADULT POPULATION: AGE AND RISK FACTORS ASSOCIATION. Cardiovascular Therapy and Prevention. 2015;14(4):44-51. (In Russ.) https://doi.org/10.15829/1728-8800-2015-4-44-51

Views: 13128


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)

101000, Moscow, Petroverigsky per., 10, str. 3
National medical research center for therapy and preventive medicine

Тел: +7 (499) 553 67 78

Editorial office Cardiovascular Therapy and Prevention

Processing of personal data
supported by NEICON (Elpub lab)