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Кардиоваскулярная терапия и профилактика

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COVID-19: состояние системы гемостаза и особенности антитромботической терапии

https://doi.org/10.15829/1728-8800-2020-2571

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Аннотация

В обзоре рассматриваются изменения показателей системы гемостаза у больных COVID-19 и анализируется их практическое значение. Рассматриваются современные подходы к профилактике и лечению тромботических/тромбоэмболических осложнений при COVID-19.

Об авторах

И. С. Явелов
ФГБУ “Национальный медицинский исследовательский центр терапии и профилактической медицины” Минздрава России
Россия
д.м.н., в.н.с. отдела клинической кардиологии


О. М. Драпкина
ФГБУ “Национальный медицинский исследовательский центр терапии и профилактической медицины” Минздрава России
Россия
д.м.н., профессор, член-корр. РАН, директор


Список литературы

1. Bikdeli B, Madhavan MV, Jimenez D, et al. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up. JACC. 2020. doi:10.1016/j.jacc.2020.04.031.

2. Kloka FA, Kruipb MJHA, van der Meerc NJM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020. doi:10.1016/j.thromres.2020.04.013.

3. Cui S, Chen S, Li X, Liu S, Wang F. Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia. J Thromb Haemost. 2020. doi:10.1111/JTH.14830.

4. Poissy J, Goutay J, Caplan M, et al. Pulmonary Embolism in COVID-19 Patients: Awareness of an Increased Prevalence. Circulation. 2020. doi:10.1161/CIRCULATIONAHA.120.047430.

5. Dolhnikoff M, Duarte-Neto AN, Monteiro RAA, et al. Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19. J Thromb Haemost. 2020. doi:10.1111/JTH.14844.

6. Carsana L, Sonzogni A, Nasr A. Pulmonary post-mortem findings in a large series of COVID-19 cases from Northern Italy. doi:10.1101/2020.04.19.20054262 https://www.medrxiv.org/content/10.1101/2020.04.19.20054262v1.

7. Thachil J, Tang N, Gando S, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19. J Thromb Haemost. 2020. doi:10.1111/jth.14810.

8. Lippi G, Plebani M, Henry BM. Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A metaanalysis. Clin Chim Acta. 2020. doi:10.1016/j.cca.2020.03.022.

9. Zhang Y, Xiao M, Zhang S. Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. N Engl J Med. 2020. doi:10.1056/NEJMc2007575.

10. Ciceri F, Beretta L, Scandroglio AM, et al. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis. Crit Care Resusc. 2020. [Epub ahead of print].

11. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18:844-7. doi:10.1111/jth.14768.

12. Tang N, Bai H, Chen X, et al. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020. doi:10.1111/JTH.14817.

13. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054-62. doi:10.1016/S0140-6736(20)30566-3.

14. Petrilli CM, Jones SA, Yang J, et al. Factors associated with hospitalization and critical illness among 4,103 patients with Covid-19 disease in New York City. doi:10.1101/2020.04.08.20057794. https://www.medrxiv.org/content/10.1101/2020.04.08.20057794v1.

15. Massachusetts General Hospital. Hematology Issues during COVID-19. Version 7.0, 4/14/2020. https://www.massgeneral.org/assets/MGH/pdf/news/coronavirus/guidance-from-massgeneral-hematology.pdf.

16. Iba T, Levy JH, Warkentin TE, et al. the Scientific and Standardization Committee on DIC, and the Scientific and Standardization Committee on Perioperative and Critical Care of the International Society on Thrombosis and Haemostasis. Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation. J Thromb Haemost. 2019;17:1989-94. doi:10.1111/jth.14578.

17. Samama MM, Cohen AT, Darmon JY, et al. A comparison of enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patients. N Engl J Med. 1999;341:793-800.

18. Cohen AT, Davidson BL, Gallus AS, et al. Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomized placebo-controlled trial. BMJ. 2006;332:325-9. doi:10.1136/bmj.38733.466748.7C.

19. Leizorovicz A, Cohen AT, Turpie AG, et al. Randomized, placebocontrolled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients. Circulation. 2004;110:874-9. doi:10.1161/01.CIR.0000138928.83266.24.

20. Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of Venous Thromboembolism. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:381S-453S. doi:10.1378/chest.08-0656.

21. Kahn SR, Lim W, Dunn AS, et al. Prevention of VTE in Nonsurgical Patients. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(suppl):e195Se226S. doi:10.1378/chest.11-2296.

22. Barbar S, Noventa F, Rossetto V, et al. A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score. J Thromb Haemost. 2010;8:2450-7. doi:10.1111/j.1538-7836.2010.04044.x.

23. Spyropoulos AC, Anderson FA, FitzGerald G, et al., for the IMPROVE Investigators. Predictive and Associative Models to Identify Hospitalized Medical Patients at Risk for VTE. Chest. 2011;140:706-14. doi:10.1378/chest.10-1944.

24. Cohen AT, Harrington RA, Goldhaber SZ, et al., for the APEX Investigators. Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients. N Engl J Med. 2016;375:534-44. doi:10.1056/NEJMoa1601747.

25. Gibson CM, Spyropoulos AC, Cohen AT, et al. The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification. TH Open. 2017;1:e56-e65. doi:10.1055/s-0037-1603929.

26. Thachil J. The versatile heparin in COVID-19. J Thromb Haemost. 2020. doi:10.1111/JTH.14821.

27. Hull RD, Schellong SM, Tapson VF, et al., for the EXCLAIM (Extended Prophylaxis for Venous ThromboEmbolism in Acutely Ill Medical Patients With Prolonged Immobilization) study. Extended-Duration Venous Thromboembolism Prophylaxis in Acutely Ill Medical Patients With Recently Reduced Mobility. A Randomized Trial. Ann Intern Med. 2010;153:8-18. doi:10.7326/0003-4819-153-1-201007060-00004.

28. Spyropoulos AC, Ageno W, Albers GW, et al., for the MARINER Investigators. Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness. Engl J Med. 2018;379:1118-27. doi:10.1056/NEJMoa1805090.

29. Moore HB, Barrett CD, Moore EE, et al. Is There a Role for Tissue Plasminogen Activator (tPA) as a Novel Treatment for Refractory COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS)? J Trauma and Acute Care Surgery. 2020. doi:10.1097/TA.0000000000002694.

30. Wang J, Hajizadeh N, Moore EE, et al. Tissue Plasminogen Activator (tPA) Treatment for COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS): A Case Series. J Thromb Haemost. 2020. doi:10.1111/JTH.14828.

31. Li J, Li Y, Yang B, et al. Low-molecular-weight heparin treatment for acute lung injury/acute respiratory distress syndrome: a meta-analysis of randomized controlled trials. Int J Clin Exp Med. 2018;11:414-22.

32. Liverpool Drug Interaction Group. Interactions with Experimental COVID-19 Therapies. https://www.covid19-druginteractions.org.

33. ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic. Last updated on 21 April 2020. https://www.escardio.org/Education/COVID-19-and-Cardiology/ESC-COVID-19-Guidance.


Для цитирования:


Явелов И.С., Драпкина О.М. COVID-19: состояние системы гемостаза и особенности антитромботической терапии. Кардиоваскулярная терапия и профилактика. 2020;19. https://doi.org/10.15829/1728-8800-2020-2571

For citation:


Yavelov I.S., Drapkina O.M. COVID-19: hemostatic parameters and specifics of antithrombotic treatment. Cardiovascular Therapy and Prevention. 2020;19. (In Russ.) https://doi.org/10.15829/1728-8800-2020-2571

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)