COVID-19: urgent questions for estimating morbidity, prevalence, case fatality rate and mortality rate
O. M. Drapkina,
I. V. Samorodskaya,
M. G. Sivtseva,
E. P. Kakorina,
N. I. Briko,
S. N. Cherkasov,
V. A. Zinserling,
P. G. Malkov https://doi.org/10.15829/1728-8800-2020-2585
Abstract
During epidemics, the usual statistical approaches will not allow determining the readiness of the public health system to take urgent measures to counteract the increase in morbidity, spread and mortality of the population. The quality of the medical, socio-economic and managerial decisions at all levels will depend on the accuracy of statistical data and the possibility of creating adequate prognostic models. However, there are still problems with the identification of COVID-19 cases and the diagnostic accuracy of the methods used. Complex analytical efforts require in order to determine the COVID-19 impact on the health status and case fatality rate/mortality rate.
About the Authors
O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Moscow
Russian Federation
Moscow
I. V. Samorodskaya
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Moscow
Russian Federation
Moscow
M. G. Sivtseva
MedInvestGroup
Russian Federation
Moscow
Russian Federation
Moscow
E. P. Kakorina
I.M. Sechenov First Moscow State Medical University
Russian Federation
Moscow
Russian Federation
Moscow
N. I. Briko
I.M. Sechenov First Moscow State Medical University
Russian Federation
Moscow
Russian Federation
Moscow
S. N. Cherkasov
N.A. Semashko National Research Institute of Public Health
Russian Federation
Moscow
Russian Federation
Moscow
V. A. Zinserling
Almazov National Medical Research Center
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
P. G. Malkov
Lomonosov Moscow State University
Russian Federation
Moscow
Russian Federation
Moscow
References
1. WHO. Coronavirus disease (COVID-19) Pandemic. Geneva: WHO. 2020. https://www.who.int/emergencies/diseases/novelcoronavirus-2019.
2. Baud D, Qi X, Nielsen-Saines K, et al. Real estimates of mortality following COVID-19 infection. Lancet Infect Dis. 2020. doi:10.1016/S1473-3099(20)30195-X.
3. Remuzzi A, Remuzzi G. COVID-19 and Italy: what next? The Lancet. 2020; 11;395(10231):1225-1228. doi:10.1016/S0140-6736(20)30627-9.
4. Parodi E, Jewkes S, Cha S, Park J. Italy and South Korea Virus Outbreaks Reveal Disparity in Deaths and Tactics. Medscape; 2020. https://www.medscape.com/viewarticle/926697.
5. Pisano GP, Sadun R, Zanini M. Lessons from Italy’s Response to Coronavirus. Harvard Business Publishing; 2020. https://hbr.org/2020/03/lessons-from-italys-response-to-coronavirus.
6. Gaziano O. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy. JAMA. 2020. doi:0.1001/jama.2020.4683.
7. WHO. Case definitions WHO periodically updates the Global Surveillance for human infection with coronavirus disease (COVID19). Geneva: WHO; 2020. https://www.who.int/docs/defaultsource/coronaviruse/situation-reports/20200323-sitrep-63-covid-19.pdf?sfvrsn=d97cb6dd_2.
8. Bischof E, Chen G, Ferretti MT. Understanding COVID-19 new diagnostic guidelines — a message of reassurance from an internal medicine doctor in Shanghai. Swiss Med Wkly. 2020;150:w20216. doi:10.4414/smw.2020.20216.
9. WHO. COVID-19 coding in ICD-10. Geneva: WHO. 2020. https://www.who.int/classifications/icd/COVID-19-coding-icd10.pdf?ua=1.
10. Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145-51. doi:10.3760/cma.j.issn.0254-6450.2020.02.003.
11. Spychalski P, Błażyńska-Spychalska A, Kobiela J. Estimating case fatality rates of COVID-19. Lancet Infect Dis. 2020. doi:10.1016/S1473-3099(20)30246-2.
12. Rajgor DD, Lee MH, Archuleta S, et al. The many estimates of the COVID-19 case fatality rate. Lancet Infect Dis. 2020. doi:10.1016/S1473-3099(20)30244-9.
13. Lipsitch M, Donnelly CA, Fraser C, et al. Potential Biases in Estimating Absolute and Relative Case-Fatality Risks during Outbreaks. PLoS Negl Trop Dis. 2015;9(7):e0003846. doi:10.1371/journal.pntd.0003846.
14. Baumgaertner E. How deadly is the new coronavirus? Scientists race to find the answer. Los Angeles Times. 2020. https://www.latimes.com/science/story/2020-02-11/how-deadly-iscoronavirus-fatality-rate.
15. Lipsitch M. Estimating case fatality rates of COVID-19. NewsMedical. 2020. doi:10.1016/S1473-3099(20)30245-0.
16. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020:S0140- 6736(20)30566-3. doi:10.1016/S0140-6736(20)30566-3.
17. Wu C, Chen X, Cai Y, et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020:e200994. doi:10.1001/jamainternmed.2020.0994.
18. Duqueroy V. COVID-19: Advice From a French Doctor on the Frontline. https://www.medscape.com/viewarticle/926883
19. Dong Y, Mo X, Hu Y, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics. 2020:pii:e20200702. doi:10.1542/peds.2020-0702.
20. Samorodskaya IV, Zajratyanc OV, Barbarash OL, Boytsov SA. Position Statement on Challenges in Assessing CauseSpecific Mortality. Kardiologiia. 2018;58(9):63-6. (In Russ.) doi:10.18087/cardio.2018.9.10178.
21. WHO. Emergency use ICD codes for COVID-19 disease outbreak. Geneva: WHO. 2020. https://www.who.int/classifications/icd/covid19/en/
22. International Guidelines for Certification and Classification (Coding) of Covid-19 as Cause of Death. 2020. https://www.who.int/classifications/icd/Guidelines_Cause_of_Death_COVID19.pdf.
23. Guidance for Certifying Deaths Due to Coronavirus Disease 2019 (COVID-19) https://www.cdc.gov/nchs/data/nvss/vsrg/vsrg03-508.pdf.
24. Guidelines for coding and selection of the underlying state in morbidity statistics and the initial cause in mortality statistics associated with COVID-19. (In Russ.) https://static-1.rosminzdrav.ru/system/attachments/attaches/000/050/527/original/27052020_MR_STAT_1.pdf
25. Tracking covid-19 excess deaths across countries. https://www.economist.com/graphic-detail/2020/04/16/tracking-covid-19-excess-deaths-across-countries.
Review
For citations:
Drapkina O.M., Samorodskaya I.V., Sivtseva M.G., Kakorina E.P., Briko N.I., Cherkasov S.N., Zinserling V.A., Malkov P.G. COVID-19: urgent questions for estimating morbidity, prevalence, case fatality rate and mortality rate. Cardiovascular Therapy and Prevention. 2020;19(3):2585. (In Russ.) https://doi.org/10.15829/1728-8800-2020-2585
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