ЭНДОТЕЛИАЛЬНЫЙ ГЛИКОКАЛИКС — ПОТЕНЦИАЛЬНЫЙ СОСУДИСТЫЙ БИОМАРКЕР: ДИАГНОСТИЧЕСКАЯ И ТЕРАПЕВТИЧЕСКАЯ МИШЕНЬ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ
https://doi.org/10.15829/1728-8800-2015-6-87-92
Аннотация
Эндотелиальный гликокаликс (ЭГК) представляет собой высокоорганизованную протективную структуру сосудистого русла. Повреждение ЭГК является одним из первых патогенетических механизмов развития различных патологий, и в первую очередь сердечно-сосудистых заболеваний. В настоящей статье представлены данные о строении, функционировании ЭГК в норме и патологии, а также о возможности использования ЭГК в качестве потенциального сосудистого биомаркера, терапевтической мишени.
Об авторах
А. Ю. Горшков
ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва
Россия
Россия
аспирант
Тел.: +7 (916) 310-91-84
С. А. Бойцов
ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва
Россия
д.м.н., профессор, директор
Россия
д.м.н., профессор, директор
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Рецензия
Для цитирования:
Горшков А.Ю., Бойцов С.А. ЭНДОТЕЛИАЛЬНЫЙ ГЛИКОКАЛИКС — ПОТЕНЦИАЛЬНЫЙ СОСУДИСТЫЙ БИОМАРКЕР: ДИАГНОСТИЧЕСКАЯ И ТЕРАПЕВТИЧЕСКАЯ МИШЕНЬ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ. Кардиоваскулярная терапия и профилактика. 2015;14(6):87-92. https://doi.org/10.15829/1728-8800-2015-6-87-92
For citation:
Gorshkov A.Yu., Boytsov S.A. ENDOTHELIAL GLYCOCALYX — POTENTIAL VASCULAR BIOMARKER: DIAGNOSTIC AND THERAPEUTIC TARGET IN CARDIOVASCULAR DISEASES. Cardiovascular Therapy and Prevention. 2015;14(6):87-92. (In Russ.) https://doi.org/10.15829/1728-8800-2015-6-87-92
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