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Cardiovascular Therapy and Prevention

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Influence of psychosocial risk factors on the course and prognosis of cardiovascular diseases

https://doi.org/10.15829/1728-8800-2022-3280

Abstract

It has now been established that psychosocial risk factors significantly worsen the course of cardiovascular diseases (CVDs) and reduce patients’ adherence to treatment. Patients with CVDs are characterized by a high prevalence of anxiety comorbidities, which can reach 50-60%. The presence of concomitant anxiety disorders seriously worsens the prognosis of CVDs. The results of studies showed that anxiety increases the risk of fatal myocardial infarction and sudden death by 1,9 times and 4,5 times, respectively. Therefore, the correction of psychosocial factors, in particular anxiety symptoms, should be an important component of the treatment of patients with CVDs. The conducted studies show that the use of fabomotizole in patients with CVD and concomitant anxiety disorders reduces the anxiety manifestations. In addition, a pronounced improvement of somatic status is recorded, which is important for improving the course and prognosis of CVDs. The accumulated experience of fabomotizole use makes it possible to recommend it for the treatment of patients with anxiety and CVDs.

About the Authors

O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Moscow



A. I. Fedin
Pirogov Russian National Research Medical University
Russian Federation

Moscow



O. A. Dorofeeva
V.V. Zakusov Research Institute of Pharmacology
Russian Federation

Moscow



V. E. Medvedev
Medical Institute of the Peoples’ Friendship University of Russia
Russian Federation

Moscow



E. N. Kareva
I.M. Sechenov First Moscow State Medical University
Russian Federation

Moscow



O. N. Dzhioeva
National Medical Research Center for Therapy and Preventive Medicine; Moscow State University of Medicine and Dentistry
Russian Federation

Moscow



S. G. Kuklin
Irkutsk State Medical Academy of Postgraduate Education, branch of Russian Medical Academy of Continuous Professional Education
Russian Federation

Irkutsk



Е. Yu. Solovieva
Pirogov Russian National Research Medical University
Russian Federation

Moscow



D. I. Abdulganieva
Kazan State Medical University
Russian Federation

Kazan



Z. F. Kim
Kazan State Medical University
Russian Federation

Kazan



M. S. Grigorovich
State Medical University
Russian Federation

Kirov



I. I. Shaposhnik
South Ural State Medical University
Russian Federation

Chelyabinsk



N. А. Koryagina
E.A. Wagner Perm State Medical University
Russian Federation

Perm



S. B. Seredenin
V.V. Zakusov Research Institute of Pharmacology
Russian Federation

Moscow



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Review

For citations:


Drapkina O.M., Fedin A.I., Dorofeeva O.A., Medvedev V.E., Kareva E.N., Dzhioeva O.N., Kuklin S.G., Solovieva Е.Yu., Abdulganieva D.I., Kim Z.F., Grigorovich M.S., Shaposhnik I.I., Koryagina N.А., Seredenin S.B. Influence of psychosocial risk factors on the course and prognosis of cardiovascular diseases. Cardiovascular Therapy and Prevention. 2022;21(5):3280. (In Russ.) https://doi.org/10.15829/1728-8800-2022-3280

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)