Bioresource collection of cell lines and primary tumors of the National Medical Research Center of Oncology of the Ministry of Health of Russia
S. V. Timofeeva,
S. Yu. Filippova,
A. O. Sitkovskaya,
N. V. Gnennaya,
I. V. Mezhevova,
T. V. Shamova,
L. M. Vashchenko,
V. E. Kolesnikov,
I. A. Novikova,
O. I. Kit https://doi.org/10.15829/1728-8800-2022-3397
Abstract
The Biobank of the National Medical Research Center of Oncology is a multi-layered infrastructure with large collections of biological samples, complemented by extensive and well-annotated clinical and pathological patient data, including medical images, pathological histology, and molecular analysis of biosamples. To date, the biobank of the National Medical Research Center of Oncology contains collections of primary and immortalized cancer cell lines of human origin. The collection of primary cell lines was formed from samples of postoperative material taken during the removal of tumors of various localizations (breast cancer, prostate cancer, lung cancer). All cell lines underwent internal quality control for contaminants (exogenous viruses, mycoplasmas and bacterial L-forms), viability and were cultivated without antibiotics. On the basis of the collected samples, a significant number of projects in the field of biomedicine were carried out, the results of which are described in this article.
About the Authors
S. V. Timofeeva
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
S. Yu. Filippova
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
A. O. Sitkovskaya
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
N. V. Gnennaya
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
I. V. Mezhevova
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
T. V. Shamova
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
L. M. Vashchenko
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
V. E. Kolesnikov
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
I. A. Novikova
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
O. I. Kit
National Medical Research Center of Oncology
Russian Federation
Russian Federation
Rostov-on-Don
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For citations:
Timofeeva S.V., Filippova S.Yu., Sitkovskaya A.O., Gnennaya N.V., Mezhevova I.V., Shamova T.V., Vashchenko L.M., Kolesnikov V.E., Novikova I.A., Kit O.I. Bioresource collection of cell lines and primary tumors of the National Medical Research Center of Oncology of the Ministry of Health of Russia. Cardiovascular Therapy and Prevention. 2022;21(11):3397. (In Russ.) https://doi.org/10.15829/1728-8800-2022-3397
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