EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE
https://doi.org/10.15829/1728-8800-2016-3-25-30
Abstract
Aim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class.
Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires assessment of life quality in patients with ischemic heart disease (IHD).
Results. It was found, that tiotriazoline improves exercise tolerance, shows strong cardioprotective effect that includes antioxidant and cytoprotection effects in IHD patients.
Conclusion. Tiotriazoline helps to reduce the mean number of angina attacks in IHD patients, as to improve mean functional class.
About the Authors
E. A. Kartashova
Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
A. A. Kastanyan
Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
M. I. Nazheva
Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
A. Yu. Zhulitov
Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
E. I. Zheleznyak
Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
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Review
For citations:
Kartashova E.A., Kastanyan A.A., Nazheva M.I., Zhulitov A.Yu., Zheleznyak E.I. EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE. Cardiovascular Therapy and Prevention. 2016;15(3):25-30. (In Russ.) https://doi.org/10.15829/1728-8800-2016-3-25-30
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