Biological age: problems and prospects. Literature review
https://doi.org/10.15829/1728-8800-2024-4254
EDN: DWZUMI
Abstract
Biological age has attracted increased attention of the medical community in recent years. It is individual for each person and currently there is no clear classification for dividing into groups that could help determine whether the rate of aging in a particular individual is normal or pathological. Today, scientists are conducting a large number of clinical and laboratory studies to find the optimal marker of biological aging that would meet all the requirements. The review aim is to analyze and summarize the available data on the mechanisms of aging, the development of novel markers of biological aging and calculators that can be used in routine practice in the future to prevent the development and progression of noncommunicable diseases.
Supporting agencies: The work was carried out within the state assignment № 123020600136-7 "Identification of early predictors of cardiovascular diseases and related conditions based on 40-year follow-up of males (results of prospective and comprehensive crosssectional studies)"
About the Authors
S. A. Berns
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
A. A. Savicheva
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
O. Yu. Isaykina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
A. V. Veremeev
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
A. Yu. Gorshkov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
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Supplementary files
- Aging is an irreversible biological process associated with the development of degenerative changes in the body and a decrease in adaptive capacity.
- The aging can proceed along a natural path (physiological process), as well as along the path of premature aging (pathological process), which in turn determines the quality of a person's life, their ability to work, the ability to participate in social life and be part of society.
What might this study add?
- Further research of aging mechanisms can contribute to a targeted approach to the development of aging markers and their use to calculate biological age.
Review
For citations:
Berns S.A., Savicheva A.A., Isaykina O.Yu., Veremeev A.V., Gorshkov A.Yu., Drapkina O.M. Biological age: problems and prospects. Literature review. Cardiovascular Therapy and Prevention. 2024;23(12):4254. (In Russ.) https://doi.org/10.15829/1728-8800-2024-4254. EDN: DWZUMI
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