Joint meeting of the Committee on Quality Longevity of Male and Female Populations and the Internal Medicine Sciences’ Council of the Department of Medical Sciences of the Russian Academy of Sciences on June 26, 2025, "Gender Approaches to Assessing the Health of the Male and Female Populations"
https://doi.org/10.15829/1728-8800-2025-4674
EDN: XMAIVQ
About the Authors
A. A. KamalovРоссия
Moscow
О. N. Tkacheva
Россия
Moscow
V. A. Bozhedomov
Россия
Moscow
L. A. Gabbasova
Россия
Moscow
O. Yu. Nesterova
Россия
Moscow
E. V. Garbuzova
Россия
Moscow
M. A. Livzan
Россия
Omsk
A. I. Ershova
Россия
Moscow
O. M. Drapkina
Россия
Moscow
References
1. Zeidan RS, McElroy T, Rathor L, et al. Sex differences in frailty among older adults. Exp Gerontol. 2023;184:112333. doi:10.1016/j.exger.2023.112333.
2. Kamalov AA, Bozhedomov VA, Gabbasova LA, et al. Gender differences in health, disease development and life expectancy and the approaches to the choice of health-saving technologies. Herald of the Russian Academy of Sciences. 2025;95(1):75-85. (In Russ.) doi:10.7868/S3034520025010079.
3. Forsyth KS, Jiwrajka N, Lovell CD, et al. The conneXion between sex and immune responses. Nat Rev Immunol. 2024;24(7):487-502. doi:10.1038/s41577-024-00996-9.
4. Krueger K, Lamenza F, Gu H, et al. Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape? Mol Cell Neurosci. 2023;125:103859. doi:10.1016/j.mcn.2023.103859.
5. Wiese CB, Avetisyan R, Reue K. The impact of chromosomal sex on cardiometabolic health and disease. Trends Endocrinol Metab. 2023;34(10):652-65. doi:10.1016/j.tem.2023.07.003.
6. Phyo AZZ, Fransquet PD, Wrigglesworth J, et al. Sex differences in biological aging and the association with clinical measures in older adults. Geroscience. 2024;46(2):1775-88. doi:10.1007/s11357-023-00941-z.
7. Bozack AK, Rifas-Shiman SL, Gold DR, et al. DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort. Clin Epigenetics. 2023;15(1):62. doi:10.1186/s13148-023-01480-2.
8. Uchehara B, Coulter Kwee L, Regan J, et al. Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy. Circ Genom Precis Med. 2023;16(3):216-23. doi:10.1161/CIRCGEN.122.003772.
9. Vasconcelos RP, Peixoto MS, de Oliveira KA, et al. Sex differences in subcutaneous adipose tissue redox homeostasis and inflammation markers in control and high-fat diet fed rats. Appl Physiol Nutr Metab. 2019;44(7):720-26. doi:10.1139/apnm-2018-0611.
10. Borrás C, Sastre J, García-Sala D, et al. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radic Biol Med. 2003; 34(5):546-52. doi:10.1016/s0891-5849(02)01356-4.
11. Antimonova OI, Galkina OV, Morozkina SN, et al. Steroid estrogens as antioxidants. Vestnik Sankt-Peterburgskogo Universiteta, Seriya 4: Fizika, Khimiya. 2012;3:79-95. (In Russ.)
12. Hägg S, Jylhävä J. Sex differences in biological aging with a focus on human studies. Elife. 2021;10:e63425. doi:10.7554/eLife.63425.
13. Mauvais-Jarvis F, Lindsey SH. Metabolic benefits afforded by estradiol and testosterone in both sexes: clinical considerations. J Clin Invest. 2024;134(17):e180073. doi:10.1172/JCI180073.
14. Wu FC, Tajar A, Pye SR, et al. Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. J Clin Endocrinol Metab. 2008;93(7):2737-45. doi:10.1210/jc.2007-1972.
15. Wu FC, Tajar A, Beynon JM, et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med. 2010;363(2):123-35. doi:10.1056/NEJMoa0911101.
16. Zarotsky V, Huang MY, Carman W, et al. Systematic literature review of the risk factors, comorbidities, and consequences of hypogonadism in men. Andrology. 2014;2(6):819-34. doi:10.1111/andr.274.
17. Banks I. No man's land: men, illness, and the NHS. BMJ. 2001; 323(7320):1058-60. doi:10.1136/bmj.323.7320.1058.
18. Dolan A. "Men give in to chips and beer too easily": how working-class men make sense of gender differences in health. Health (London). 2014;18(2):146-62. doi:10.1177/1363459313488004.
19. Kamalov AA, Gabbasova LA, Nesterova OYu, et al. Men’s health preservation: gender-specific features of disease prevention and choice of program solutions. Urologiia. 2024;6:125-133. (In Russ.)
20. Karamnova NS, Maksimov SA, Kapustina AV, et al. High salt intake in the Russian population: prevalence, regional aspects, associations with socio-demographic characteristics, risk factors and diseases. Results of epidemiological studies ESSE-RF and EGIDA-Moscow. Cardiovascular Therapy and Prevention. 2023;22(12):3827. (In Russ.) doi:10.15829/1728-8800-2023-3827.
21. Balanova YuA, Drapkina OM, Kutsenko VA, et al. Obesity in the Russian population during the COVID-19 pandemic and associated factors. Data from the ESSE-RF3 study. Cardiovascular Therapy and Prevention. 2023;22(8S):3793. (In Russ.) doi:10.15829/1728-8800-2023-3793.
22. Balanova YuA, Drapkina OM, Kutsenko VA, et al. Hypertension in the Russian population during the COVID-19 pandemic: sex differences in prevalence, treatment and its effectiveness. Data from the ESSE-RF3 study. Cardiovascular Therapy and Prevention. 2023;22(8S):3785. (In Russ.) doi:10.15829/1728-8800-2023-3785.
23. Drapkina OM, Imaeva AE, Kutsenko VA, et al. Dyslipidemia in the Russian Federation: population data, associations with risk factors. Cardiovascular Therapy and Prevention. 2023;22(8S):3791. (In Russ.) doi:10.15829/1728-8800-2023-3791.
24. Rehman A, Lathief S, Charoenngam N, et al. Aging and Adiposity-Focus on Biological Females at Midlife and Beyond. Int J Mol Sci. 2024;25(5):2972. doi:10.3390/ijms25052972.
25. Cavazos-Rehg PA, Krauss MJ, Spitznagel EL, et al. Maternal age and risk of labor and delivery complications. Matern Child Health J. 2015;19(6):1202-11. doi:10.1007/s10995-014-1624-7.
26. Bellamy L, Casas JP, Hingorani AD, et al. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ. 2007;335(7627):974. doi:10.1136/bmj.39335.385301.BE.
27. Herath H, Herath R, Wickremasinghe R. Gestational diabetes mellitus and risk of type 2 diabetes 10 years after the index pregnancy in Sri Lankan women-A community based retrospective cohort study. PLoS One. 2017;12(6):e0179647. doi:10.1371/journal.pone.0179647.
28. Qiu C, Hevner K, Abetew D, et al. Mitochondrial DNA copy number and oxidative DNA damage in placental tissues from gestational diabetes and control pregnancies: a pilot study. Clin Lab. 2013;59(5-6):655-60. doi:10.7754/clin.lab.2012.120227.
29. Li W, Liu H, Qiao Y, et al. Metabolic syndrome of weight change from pre-pregnancy to 1-5 years post-partum among Chinese women with prior gestational diabetes. Diabet Med. 2015;32(11):1492-9. doi:10.1111/dme.12790.
30. Peng Q, Karvonen-Gutierrez CA, Randolph JF, et al. Age at Onset of Metabolic Syndrome Among Women With and Without Polycystic Ovary Syndrome-Like Status. J Clin Endocrinol Metab. 2019;104(5):1429-39. doi:10.1210/jc.2018-01428.
31. Jensterle M, Weber M, Pfeifer M, et al. Assessment of insulin resistance in young women with polycystic ovary syndrome. Int J Gynaecol Obstet. 2008;102(2):137-40. doi:10.1016/j.ijgo.2008.03.017.
32. Ollila MM, Hoek A, Piltonen TT. The association between polycystic ovary syndrome and early cardiovascular disease morbidity strengthens. Eur J Endocrinol. 2023;189(1):R4-R5. doi:10.1093/ejendo/lvad083.
33. Chang Y, Cho B, Kim S, et al. Direct conversion of fibroblasts to osteoblasts as a novel strategy for bone regeneration in elderly individuals. Exp Mol Med. 2019;51(5):1-8. doi:10.1038/s12276-019-0251-1.
34. Critchlow AJ, Hiam D, Williams R, et al. The role of estrogen in female skeletal muscle aging: A systematic review. Maturitas. 2023;178:107844. doi:10.1016/j.maturitas.2023.107844.
35. Rinaldi F, Trink A, Mondadori G, et al. The Menopausal Transition: Is the Hair Follicle "Going through Menopause"? Biomedicines. 2023;11(11):3041. doi:10.3390/biomedicines11113041.
36. Lephart ED, Naftolin F. Factors Influencing Skin Aging and the Important Role of Estrogens and Selective Estrogen Receptor Modulators (SERMs). Clin Cosmet Investig Dermatol. 2022;15:1695-709. doi:10.2147/CCID.S333663.
37. Kuznetsov MR, Papysheva OV, Orlov BB, Sorokina IV. Hormones and Vessels: Pros and Cons. Doctor.Ru. 2020;19(6):85-90. (In Russ.) doi:10.31550/1727-2378-2020-19-6-85-90.
38. Barth C, de Lange AG. Towards an understanding of women's brain aging: the immunology of pregnancy and menopause. Front Neuroendocrinol. 2020;58:100850. doi:10.1016/j.yfrne.2020.100850.
39. Cohen A, Pieper CF, Brown AJ, et al. Number of children and risk of metabolic syndrome in women. J Womens Health (Larchmt). 2006;15(6):763-73. doi:10.1089/jwh.2006.15.763.
40. Sood R, Faubion SS, Kuhle CL, et al. Prescribing menopausal hormone therapy: an evidence-based approach. Int J Womens Health. 2014;6:47-57. doi:10.2147/IJWH.S38342.
41. Lampiao F. "It is time the masses are sensitize that men too, like women have reproductive problems ...". Interview by Thengo Kavinya. Malawi Med J. 2012;24(4):95.
42. Korneev IA, Apolikhin OI, Babenko AYu, et al. (Working Group on the Development of Russian Clinical Guidelines for Male Infertility). Clinical guidelines for male infertility: debatable issues and the need for an interdisciplinary consensus. Urologiia. 2024;(1):143-52. (In Russ.) doi:10.18565/urology.2024.1.143-152.
43. Schlegel PN, Sigman M, Collura B, et al. Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline Part I. J Urol. 2021;205(1):36-43. doi:10.1097/JU.0000000000001521.
44. Infertility prevalence estimates, 1990 — 2021. Geneva: World Health Organization; 2023. ISBN: 978-92-4-006831-5 (electronic version).
45. Agarwal A, Majzoub A, Baskaran S, et al. Sperm DNA Fragmentation: A New Guideline for Clinicians. World J Mens Health. 2020;38(4):412-71. doi:10.5534/wjmh.200128.
46. Esteves SC, Roque M, Bradley CK, et al. Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen: systematic review and meta-analysis. Fertil Steril. 2017;108(3):456-67. doi:10.1016/j.fertnstert.2017.06.018.
47. Ojo OA, Nwafor-Ezeh PI, Rotimi DE, et al. Apoptosis, inflammation, and oxidative stress in infertility: A mini review. Toxicology reports. 2023;10:448-62. doi:10.1016/j.toxrep.2023.04.006.
48. Meinhardt A. Andrology 3rd edition. E. Nieschlag, H. M. Behre, S. Nieschlag (eds). Asian J Androl. 2010;12(3):458. doi:10.1038/aja.2010.27.
49. Barratt CLR, Björndahl L, De Jonge CJ, et al. The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities. Hum Reprod Update. 2017;23(6):660-80. doi:10.1093/humupd/dmx021.
Review
For citations:
Kamalov A.A., Tkacheva О.N., Bozhedomov V.A., Gabbasova L.A., Nesterova O.Yu., Garbuzova E.V., Livzan M.A., Ershova A.I., Drapkina O.M. Joint meeting of the Committee on Quality Longevity of Male and Female Populations and the Internal Medicine Sciences’ Council of the Department of Medical Sciences of the Russian Academy of Sciences on June 26, 2025, "Gender Approaches to Assessing the Health of the Male and Female Populations". Cardiovascular Therapy and Prevention. 2025;24(12):4674. (In Russ.) https://doi.org/10.15829/1728-8800-2025-4674. EDN: XMAIVQ
JATS XML

















































