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Cardiovascular Therapy and Prevention

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Supply of vitamins for patients with type 2 diabetes and obesity in the autumn

https://doi.org/10.15829/1728-8800-2019-1-95-101

Abstract

Aim. To assess the availability of patients with type 2 diabetes mellitus (DM-2) and obesity with vitamins C, A, E, D, B2, B6, niacin and betacarotene.

Material and methods. We assess vitamin status of 40 patients with DM-2 (14 men and 26 women) aged 42-80 years was 60,2±1,3 (Me=60,5) with concomitant obesity and a body mass index from 31,2 to 57,4 kg 42,1±1,1 (Me=42,0), receiving oral hypoglycemic therapy. The disease duration ranged from six months to 32 years — 7,4±1,0 (Me=6,0), the level of glycohemoglobin — from 5,20% to 7,70% — 6,27±0,11 (Me=6,05). The provision of C, A, E, D, B2 vitamins and beta-carotene was assessed by their serum concentration, B6 and niacin vitamins — by excretion of their metabolites with urine.

Results. Against the background of a good supply of patients with A, E, C and PP vitamins, a reduced serum concentration of 25-OH vitamin D was detected in the majority (83%) of the patients, beta carotene — in 55%, insufficient provision with vitamins B6 and B2 — 15-18%. A reduced serum concentration of 1-2 vitamins was detected in 65% of the patients. A combined deficiency of 3-4 vitamins had 25% of patients.

Conclusion. The presence of vitamin deficiencies in patients with DM-2, which are a risk factor for its occurrence and the development of complications, indicates the need to optimize vitamin status. The negative association between the level of basal glycemia in venous blood and glucosuria and the concentration of γ-tocopherol may indicate certain benefits of using dietary oils with a high level of vitamer.

About the Authors

N. A. Beketova
Scientific Research Institute of Nutrition
Russian Federation
Moscow


O. V. Kosheleva
Scientific Research Institute of Nutrition
Russian Federation
Moscow


O. A. Vrzhesinskaya
Scientific Research Institute of Nutrition
Russian Federation
Moscow


V. M. Kodentsova
Scientific Research Institute of Nutrition
Russian Federation
Moscow


H. H. Sharafetdinov
Scientific Research Institute of Nutrition; Russian Medical Academy of Postgraduate Education; I. M. Sechenov First Moscow State Medical University
Russian Federation
Moscow


O. A. Plotnikova
Scientific Research Institute of Nutrition
Russian Federation
Moscow


V. V. Pilipenko
Scientific Research Institute of Nutrition
Russian Federation
Moscow


R. I. Alekseeva
Scientific Research Institute of Nutrition
Russian Federation
Moscow


S. N. Leonenko
Scientific Research Institute of Nutrition
Russian Federation
Moscow


A. A. Sokolnikov
Scientific Research Institute of Nutrition
Russian Federation
Moscow


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Review

For citations:


Beketova N.A., Kosheleva O.V., Vrzhesinskaya O.A., Kodentsova V.M., Sharafetdinov H.H., Plotnikova O.A., Pilipenko V.V., Alekseeva R.I., Leonenko S.N., Sokolnikov A.A. Supply of vitamins for patients with type 2 diabetes and obesity in the autumn. Cardiovascular Therapy and Prevention. 2019;18(1):95-101. (In Russ.) https://doi.org/10.15829/1728-8800-2019-1-95-101

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)