Heart diastolic dysfunction in patients with familial arterial hypertension
Abstract
Aim. To assess heart diastolic function in patients with familial arterial hypertension (AH).
Material and methods. Echocardiography was performed in 103 individuals with familial AH and their relatives.
Results. Heart diastolic dysfunction was registered in 80% of the patients and 40% of their relatives. ACE inhibitors and diuretics were used for AH treatment. In patients with familial AH, treatment efficacy manifested in regression of left ventricular (LV) hypertrophy.
Conclusion. Patients with familial AH typically had concentric LV hypertrophy, and early developing myocardial diastolic dysfunction. Up to 40% of their relatives had signs of LV diastolic dysfunction, that must be remembered during medico-genetic consulting.
About the Authors
B. A. Namakanov
Moscow State Pedagogical University, Moscow
Russian Federation
Russian Federation
M. M. Rasulov
Moscow State Pedagogical University, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Namakanov B.A., Rasulov M.M. Heart diastolic dysfunction in patients with familial arterial hypertension. Cardiovascular Therapy and Prevention. 2005;4(3, ч.II):27-30. (In Russ.)
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