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Cardiovascular Therapy and Prevention

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Statin choice for lipid6lowering therapy: clinical pharmacology and evidence-based medicine position

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Abstract

The features of various statins’ use are analysed taking into consideration their clinical and pharmacological parameters. The present evidence base on atorvastatin and rosuvastatin is emphasised. The author compares various statins in regard to their potential in atherosclerotic plaque reduction, according to intravascular ultrasound data. Substantial benefits of lipid-lowering monotherapy by “new” vs “old” statins are demonstrated.

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Nedogoda S.V. Statin choice for lipid6lowering therapy: clinical pharmacology and evidence-based medicine position. Cardiovascular Therapy and Prevention. 2008;7(1):112-115. (In Russ.)

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)