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Кардиоваскулярная терапия и профилактика

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ГЕНЫ-КАНДИДАТЫ РЕЗИСТЕНТНОСТИ К АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЕ И ИХ СВЯЗЬ С РИСКОМ РАЗВИТИЯ СЕРДЕЧНО-СОСУДИСТЫХ КАТАСТРОФ

https://doi.org/10.15829/1728-8800-2013-1-67-72

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Аннотация

В обзоре представлены современные данные мировой литературы о наиболее вероятных полиморфизмах генов резистентности к аспирину. Таких как: полиморфизмы циклооксигеназы, гликопро- теинов GP Ib/IIIa, GP Ibα, GP VI аденозиндифосфат рецепторов P2Y1, P2Y12. Рассмотрена частота распространения полиморфизмов при лабораторной аспирин-резистентности, связь данных полиморфизмов с развитием неблагоприятных сердечно-сосудистых событий на фоне приема аспирина. 

Об авторах

Ю. И. Гринштейн
ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого Минздрава России», Красноярск
Россия

доктор медицинских наук, профессор, заведующий кафедрой терапии ИПО

Тел.: 8 (391) 2642718



А. А. Косинова
ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого Минздрава России», Красноярск
Россия
аспирант кафедры


И. Ю. Гринштейн
ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого Минздрава России», Красноярск
Россия
кандидат медицинских наук, докторант кафедры поликлинической терапии


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Для цитирования:


Гринштейн Ю.И., Косинова А.А., Гринштейн И.Ю. ГЕНЫ-КАНДИДАТЫ РЕЗИСТЕНТНОСТИ К АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЕ И ИХ СВЯЗЬ С РИСКОМ РАЗВИТИЯ СЕРДЕЧНО-СОСУДИСТЫХ КАТАСТРОФ. Кардиоваскулярная терапия и профилактика. 2013;12(1):67-72. https://doi.org/10.15829/1728-8800-2013-1-67-72

For citation:


Grinshtein Y.I., Kosinova A.A., Grinshtein I.Y. ASPIRIN RESISTANCE CANDIDATE GENES AND THEIR ASSOCIATION WITH THE RISK OF CARDIOVASCULAR EVENTS. Cardiovascular Therapy and Prevention. 2013;12(1):67-72. (In Russ.) https://doi.org/10.15829/1728-8800-2013-1-67-72

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)