Clinico-angiographic parallels in patients with coronary atherosclerosis risk factors

Abstract

Aim. To compare clinical and coronaroangiography results in patients with coronary atherosclerosis risk factors (RF). Material and methods. The study included 124 patients with coronary atherosclerosis RF. All participants were divided into four clinical groups. Group I included 66 patients with negative maximal stress tests (ST). Group II included 10 males with overt isolated painless myocardial ischemia (IPMI). Group III consisted of 14 patients with coronary heart disease (CHD), with mildly manifested stable effort angina (SEA). Group IV included 34 CHD patients with overt angina syndrome. All participants underwent selective coronaroangiography (CAG). Results. In 42.2% of patients with negative ST results, hemodynamically significant (at least, 75%) stenosis of one or more main coronary arteries (CA) was observed. According to CAG data, all CHD patients had hemodynamically significant CA pathology. In IPMI individuals, one main CA lesion was most prevalent; two-vessel pathology was typical for patients with mildly manifested SEA, and three-vessel pathology was prevalent in participants with overt angina syndrome. Conclusion. There was a clear link between chromic CHD clinics and CA obstruction severity. IPMI and SEA were two consequent stages in stenosing coronary atherosclerosis progression.