Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients
Abstract
Sudden cardiac death (SCD) remains the principal cause of coronary heart disease (CHD) deaths. Therefore, studying SCD mechanisms, implementing new prognostic and preventive approaches are the main aims of modern cardiology. The review analyzes modern approaches to myocardial electrical instability correction and prognosis improvement in CHD patients. It has been proved that among all antiarrhythmics, beta-adrenoblockers only, and perhaps amiodaron, can reduce SCD incidence. Total mortality and SCD rate reduction has been demonstrated for ACE inhibitors, aspirin, statins, aldosterone antagonists. Recent clinical trials have proved that implanted cardioverters-defibrillators are more effective than pharmaceutical treatment in SCD prevention among high-risk patients.
About the Authors
V. V. Popov
Moscow State Medico-Stomatological University, Central Hospital No. 6, Russian Railways Company, Moscow
Russian Federation
Russian Federation
A. E. Radzevich
Moscow State Medico-Stomatological University, Central Hospital No. 6, Russian Railways Company, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Popov V.V., Radzevich A.E. Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients. Cardiovascular Therapy and Prevention. 2007;6(3):106-115. (In Russ.)
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