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Кардиоваскулярная терапия и профилактика

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Роль низкомолекулярных гепаринов при тромболитической терапии у больных инфарктом миокарда

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Аннотация

В настоящее время стандартным дополнением к тромболитической терапии (ТЛТ) при инфаркте миокарда рассматривают парентеральное введение антикоагулянтов. В обзоре анализируются результаты клинических исследований, доказавших преимущество подкожного введения низкомолекулярного гепарина эноксапарина в течение 1 недели перед 48-часовой внутривенной инфузией нефракционированного гепарина, ставшие основой для современных представлений об оптимальном применении гепарина в случаях, когда для восстановления кровотока по окклюзированной коронарной артерии исполь­зуется ТЛТ.

Об авторе

И. С. Явелов
ГОУ ВПО Российский государственный медицинский университет
Россия

Профессор кафедры клинической фармакологии с курсом клинической кардиологии и фармакокинетики.

Москва


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Для цитирования:


Явелов И.С. Роль низкомолекулярных гепаринов при тромболитической терапии у больных инфарктом миокарда. Кардиоваскулярная терапия и профилактика. 2009;8(6):111-122.

For citation:


Yavelov I.S. Low-molecular heparins in thrombolytic therapy of myocardial infarction patients. Cardiovascular Therapy and Prevention. 2009;8(6):111-122. (In Russ.)

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