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Cardiovascular Therapy and Prevention

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Vitamin D role in arterial hypertension development

https://doi.org/10.15829/1728-8800-2012-3-77-81

Abstract

Recently obtained data have identified potential mechanisms linking D-endocrine system and blood pressure regulation. Vitamin D deficiency is associated with calcium metabolism disregulation, increased tonus of renin-angiotensin-aldosterone system, endothelial dysfunction, and metabolic syndrome development. The evidence presented suggests a possibility for developing a new, vitamin D-derived class of antihypertensive medications. This review discusses the mechanisms of arterial hypertension development which are related to vitamin D metabolism in humans.

About the Authors

E. N. Dudinskaya
State Research Centre for Preventive Medicine, Moscow
Russian Federation


O. N. Tkacheva
State Research Centre for Preventive Medicine, Moscow
Russian Federation


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Review

For citations:


Dudinskaya E.N., Tkacheva O.N. Vitamin D role in arterial hypertension development. Cardiovascular Therapy and Prevention. 2012;11(3):77-81. (In Russ.) https://doi.org/10.15829/1728-8800-2012-3-77-81

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)