Роль вазодилатирующих β-адреноблокаторов в терапии пациентов с осложненной гипертензией: фокус на небиволол
https://doi.org/10.15829/1728-8800-2011-6-94-98
Аннотация
Несмотря на доказанную эффективность β-адреноблокаторов (β-АБ) в снижении риска заболеваемости и смертности, их применение у пациентов с сопутствующей сердечно-сосудистой патологией остается ограниченным. Недостаточно частое назначение β-АБ может быть связано с опасениями, основанными на плохой переносимости старых представителей этого класса препаратов. β-АБ с вазодилатирующими свойствами, такие как карведилол и небиволол, обладают лучшей переносимостью и не вызывают неблагоприятные метаболические эффекты, в отличие от традиционных β-АБ. Поскольку эндотелиальная дисфункция как ведущая патофизиологическая характеристика артериальной гипертензии (АГ) сильнее выражена в клинических популяциях, плохо реагирующих на терапию АГ (например, у пожилых и пациентов афро-американского происхождения), вазодилатирующие β-АБ могут стать наиболее показанными препаратами при лечении таких больных.
Об авторе
Т. Д. Жиль
Отделение медицины, медицинская школа Университета Тулана
Соединённые Штаты Америки
Соединённые Штаты Америки
Новый Орлеан
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Рецензия
Для цитирования:
Жиль Т.Д. Роль вазодилатирующих β-адреноблокаторов в терапии пациентов с осложненной гипертензией: фокус на небиволол. Кардиоваскулярная терапия и профилактика. 2011;10(6):94-98. https://doi.org/10.15829/1728-8800-2011-6-94-98
For citation:
Giles T.D. The role of vasodilating β-blockers in patients with complicated hypertension: focus on nebivolol. Cardiovascular Therapy and Prevention. 2011;10(6):94-98. (In Russ.) https://doi.org/10.15829/1728-8800-2011-6-94-98
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