“Female issue” in cardiology

Aim. To study the effects of hormonal replacement therapy (HRT) with a combined medication (1 mg 17В-estradiol and 2 mg drospirenone; Angeliq) among women in early post-menopause. Material and methods. In total, 30 postmenopausal patients with climacteric syndrome were examined and prescribed HRT. The following parameters were studied: blood pressure (BP) level, vegetative disorder severity, visceral obesity, metabolic status after 6 months of Angeliq therapy, microcirculation (MC) and carotid artery intima-media thickness (IMT) after 1 year of Angeliq therapy. Results. After 6 months of the treatment, BP level was reduced, metabolic status improved, and vegetative disorders were less severe. After 1 year, MC parameters improved, and carotid IMT levels were reduced. Conclusion. Angeliq demonstrated vegeto-corrective and antihypertensive effects, together with improvement in metabolic status, visceral obesity, MC, and carotid IMT parameters among female patients in early postmenopause.

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