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Кардиоваскулярная терапия и профилактика

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Анемия и хроническая сердечная недостаточность

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Аннотация

В настоящее время уделяют большое внимание сочетанию хронической сердечной недостаточности (ХСН) с анемией, которая ухудшает течение СН и неблагоприятно влияет на прогноз. Основным звеном в развитии анемии при ХСН является абсолютная или относительная недостаточность эритропоэтина, обусловленная влиянием провоспалительных цитокинов, а также почечная дисфункция. Работы последних лет показали, что коррекция даже умеренной анемии при ХСН повышает толерантность к физическим нагрузкам, снижает функциональный класс ХСН (NYHA), улучшает качество жизни, структурнофункциональные показатели сердца, уменьшает потребность в диуретиках и числе госпитализаций. Однако отсутствуют данные о влиянии коррекции анемии на долгосрочную выживаемость пациентов, а также уровне гемоглобина, при котором следует начинать коррекцию анемии, и целевых значениях гемоглобина, безопасных для каждого пациента.

Об авторах

Т. А. Казанцева
Российский университет дружбы народов. Москва
Россия
аспирант кафедры факультетской терапии


Раджеш Раджан
Российский университет дружбы народов. Москва
Россия
аспирант кафедры пропедевтики внутренних болезней


М. А. Ефремовцева
Российский университет дружбы народов. Москва
Россия
доцент кафедры пропедевтики внутренних болезней


Л Г. Александрия
Российский университет дружбы народов. Москва
Россия
доцент кафедры факультетской терапии


Ж. Д. Кобалава
Российский университет дружбы народов. Москва
Россия
зав.кафедрой пропедевтики внутренних болезней


В. С. Моисеев
Российский университет дружбы народов. Москва
Россия
зав.кафедрой факультетской терапии


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Для цитирования:


Казанцева Т.А., Раджан Р., Ефремовцева М.А., Александрия Л.Г., Кобалава Ж.Д., Моисеев В.С. Анемия и хроническая сердечная недостаточность. Кардиоваскулярная терапия и профилактика. 2010;9(4):116-123.

For citation:


Kazantseva T.A., Radjan R., Efremovtseva M.A., Alexandriya L.G., Kobalava Z.D., Moiseev V.S. Anaemia and chronic heart failure. Cardiovascular Therapy and Prevention. 2010;9(4):116-123. (In Russ.)

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ISSN 2619-0125 (Online)