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Cardiovascular Therapy and Prevention

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Type 2 myocardial infarction: the potential for early detection

https://doi.org/10.15829/1728-8800-2023-3474

Abstract

Aim. To evaluate the potential of using factors associated with type 2 myocardial infarction (MI) for its early diagnosis.

Material and methods. This prospective study included 204 patients diagnosed with acute coronary syndrome (ACS). At the time of admission, each patient underwent standard examinations for ACS patients. The 1-year stage consisted of telephone survey of patients on the course of long-term postinfarction period. There were following endpoints: death, recurrent coronary events and hospitalization.

Result. Patients with type 2 MI accounted for 10,8% (n=22) of the entire analyzed sample. A model for prehospital diagnosis of probable type 2 MI has been developed. The model included clinical and history data that allow to suggest the type 2 MI course without invasive and laboratory studies. The model included signs (body mass index ≥35, kg/m2, atrial fibrillation+Killip I, hemoglobin <110 g/l within 1 year before MI, chronic obstructive pulmonary disease), the most common in type 2 MI patients according to own data and previous studies.

Conclusion. A model of prehospital clinical assessment of MI risk has been developed for making a preliminary diagnosis and forming different patient streams at the admission stage for the final verification of the diagnosis.

About the Authors

V. N. Karetnikova
Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical University
Russian Federation

Victoria N. Karetnikova - PhD, Professor at the Department of Cardiology and Cardiovascular Surgery; Head of the Laboratory of Circulatory Pathology.

Kemerovo



A. V. Motova
Kemerovo State Medical University
Russian Federation

Anna V. Motova - Postgraduate Student at the Department of Cardiology and Cardiovascular Surgery.

Kemerovo



A. V. Osokina
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Anastasiya V. Osokina - PhD, Senior Researcher at the Laboratory of Circulatory Pathology.

Kemerovo



D. P. Golubovskaia
Kemerovo State Medical University
Russian Federation

Daria P. Golubovskaya - Postgraduate Student.

Kemerovo



I. R. Oleinik
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Irina R. Oleinik - Postgraduate Student.

Kemerovo



E. A. Schmidt
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Evgenia A. Schmidt - PhD, leading researcher at the Laboratory of Circulatory Pathology.

Kemerovo



I. I. Zhidkova
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Irina I. Zhidkova - PhD, Researcher at the Laboratory of Circulatory Pathology.

Kemerovo



T. B. Pecherina
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Tаmara B. Pecherina - PhD, Senior Researcher at the Laboratory of Circulatory Pathology.

Kemerovo



O. M. Polikutina
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Olga M. Polikutina - PhD, Leading Researcher, Laboratory of Radiation Diagnostic Methods.

Kemerovo



O. L. Barbarash
Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical University
Russian Federation

Olga L. Barbarash - Head of the Department of Cardiology and Cardiovascular Surgery, Kemerovo State Medical University of the Ministry of Healthcare of the Russian Federation; Academician of the Russian Academy of Sciences, corresponding member of the Russian Academy of Sciences Professor, Director of Research Institute NII KPSSZ.

Kemerovo



References

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2. Reznik EV, Golubev YY, Mikhaleva LM. Diagnostics and management of patients with type 2 myocardial infarction. Consilium Medicum. 2021;23(10):765-71. (In Russ.) doi:10.26442/20751753.2021.10.201129.

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Supplementary files

What is already known about the subject?

  • The basis for type 2 myocardial infarction (MI) is a sig­nificant ischemic imbalance between myo­car­dial oxygen demand and delivery in the absence of coro­nary artery thrombosis.
  • The main immediate causes of ischemic imbalance are arrhythmias with severe tachy- or bradysystole, anemia, respiratory failure, and others.

What might this study add?

  • A model for the early diagnosis of type 2 MI based on clinical and anamnestic risk factors has been created.
  • The developed model is a tool for early prehospital diagnosis of type 2 MI and makes it possible to create different patient streams for the final diagnosis verification.

Review

For citations:


Karetnikova V.N., Motova A.V., Osokina A.V., Golubovskaia D.P., Oleinik I.R., Schmidt E.A., Zhidkova I.I., Pecherina T.B., Polikutina O.M., Barbarash O.L. Type 2 myocardial infarction: the potential for early detection. Cardiovascular Therapy and Prevention. 2023;22(3):3474. (In Russ.) https://doi.org/10.15829/1728-8800-2023-3474

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)