Microcirculation in heart failure: state of the art (literature review)
https://doi.org/10.15829/17288800-2024-4122
EDN: EIYHYT
Abstract
Microcirculatory vessels make up about 99% of all vessels in the human body, so cardiovascular diseases at different stages affect microcirculation to varying degrees. The literature review presents studies of different years on microcirculation in heart failure (HF) using the following most popular methods: laser Doppler flowmetry, polarography, nailfold capillaroscopy, bulbar conjunctiva biomicroscopy, and in vitro laboratory tests. Taking into account the changed modern concept of HF and the classification adopted in recent years that assesses the left ventricular ejection fraction, the list of cited works shows gaps in data on microcirculation changes in chronic HF with preserved ejection fraction and prospects for further related research.
About the Authors
I. M. Davidovich
Far Eastern State Medical University
Russian Federation
Russian Federation
Khabarovsk
N. V. Korneeva
Far Eastern State Medical University
Russian Federation
Russian Federation
Khabarovsk
G. A. Kovaleva
Far Eastern State Medical University
Russian Federation
Russian Federation
Khabarovsk
Yu. L. Fedorchenko
Far Eastern State Medical University
Russian Federation
Russian Federation
Khabarovsk
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Supplementary files
What is already known about the subject?
- The available information on microcirculation in patients with heart failure (HF) was obtained mainly in the study of patients with a reduced left ventricular ejection fraction (EF).
- Due to the relatively recent identification of HF phenotype with preserved EF, there is practically no data on systemic microcirculation in such patients.
What might this study add?
- The gaps in the available information on microcirculation in HF with preserved EF are shown.
- The potential of imaging techniques in the study of microcirculation in HF with preserved EF are outlined, including for assessing the effect of modern drugs recommended for the treatment of these patients.
Review
For citations:
Davidovich I.M., Korneeva N.V., Kovaleva G.A., Fedorchenko Yu.L. Microcirculation in heart failure: state of the art (literature review). Cardiovascular Therapy and Prevention. 2024;23(12):4122. (In Russ.) https://doi.org/10.15829/17288800-2024-4122. EDN: EIYHYT
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