Arrhythmias in individuals with valvular heart disease. Opinion on the problem
https://doi.org/10.15829/17288800-2025-4276
EDN: ODZMMU
Abstract
Acquired valvular heart defects are a rapidly growing cause of increased global cardiovascular morbidity and mortality with a diverse and changing geographic distribution. In addition to the direct impact on intracardiac hemodynamics, heart valve defects cause various arrhythmias. Studies have shown that even minor changes in the structure and function of the valves, in particular, mitral valve prolapse, can lead to life-threatening arrhythmias. The article discusses the most common types of valvular heart disease among adults, epidemiological issues, pathogenesis features, and modern views on their correction. Arrhythmias associated with valvular heart defects, the potential of their drug and non-drug therapy in the light of modern research are analyzed.
About the Authors
B. U. Mardanov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
M. N. Mamedov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Moscow
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Supplementary files
What is already known about the subject?
- Global aging of the population, on the one hand, and the increase in the incidence and prevalence of rheumatic heart disease, on the other, contribute to an increase in the number of patients with acquired heart defects.
- Conducting large epidemiological studies on prevalence of heart defects is associated with a number of difficulties. The latter relate to the polymorphic and long-term silent clinical performance of the disease, as well as the lack of a unified approach to inclusion in studies.
What might this study add?
- It has been shown that even minor valve damage can be accompanied by heart overload, thereby creating arrhythmogenic conditions, and complicated by hemodynamically significant and even fatal arrhythmias.
- Related drug therapy is based on the types and mechanisms of arrhythmias, regardless of the type of heart defect.
- The effectiveness and safety of surgical and catheter methods of treating arrhythmias remain controversial.
Review
For citations:
Mardanov B.U., Mamedov M.N. Arrhythmias in individuals with valvular heart disease. Opinion on the problem. Cardiovascular Therapy and Prevention. 2025;24(7):4276. (In Russ.) https://doi.org/10.15829/17288800-2025-4276. EDN: ODZMMU
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