Microcirculation assessment using capillaroscopy in cardiology
N. V. Lishuta,
M. V. Kozhevnikova,
O. A. Slepova,
Yu. N. Belenkov,
A. A. Simanovsky,
V. A. Shakhnovich,
F. N. Mustafina https://doi.org/10.15829/1728-8800-2025-4380
EDN: MQTLQN
Abstract
The development and progression of cardiovascular diseases is accompanied by various changes at all vascular levels, from large arteries to capillaries. This makes it especially important to study various approaches to diagnosing vascular lesions. Particular attention is drawn to non-invasive research methods that have wide potential for assessing microcirculatory disorders. Of greatest interest is capillaroscopy, which can be used to assess both structure and function. The article discusses the current status of microcirculation assessment and the potential of capillaroscopy in diagnosing various disorders in patients with cardiovascular disease.
About the Authors
N. V. Lishuta
Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Moscow
M. V. Kozhevnikova
Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Moscow
O. A. Slepova
Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Moscow
Yu. N. Belenkov
Sechenov First Moscow State Medical University;
Dr. Shakhnovich Neurology Center
Russian Federation
Russian Federation
Moscow
A. A. Simanovsky
ФГАОУ ВО "Первый МГМУ им. И. М. Сеченова" Минздрава России (Сеченовский Университет);
ООО "Центр неврологии доктора Шахновича"
Russian Federation
Russian Federation
Moscow
V. A. Shakhnovich
Dr. Shakhnovich Neurology Center
Russian Federation
Russian Federation
Moscow
F. N. Mustafina
Dr. Shakhnovich Neurology Center
Russian Federation
Russian Federation
Moscow
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Supplementary files
What is already known about the subject?
- Microcirculatory disorders play a key role in the pathogenesis of cardiovascular diseases (CVD), including coronary artery disease and hypertension.
- Capillaroscopy makes it possible to evaluate the structural and functional parameters of capillaries, but requires standardization.
- A decrease in capillary network density correlates with the risk of cardiovascular events, such as myocardial infarction and organ dysfunction.
What might this study add?
- The study emphasizes the clinical significance of capillaroscopy for early diagnosis of microcirculatory disorders in patients with CVD.
- Artificial intelligence algorithms for analyzing capillaroscopy data should be implemented.
- Prognostic value of capillary system changes as markers of disease progression is showed.
Review
For citations:
Lishuta N.V., Kozhevnikova M.V., Slepova O.A., Belenkov Yu.N., Simanovsky A.A., Shakhnovich V.A., Mustafina F.N. Microcirculation assessment using capillaroscopy in cardiology. Cardiovascular Therapy and Prevention. 2025;24(8):4380. (In Russ.) https://doi.org/10.15829/1728-8800-2025-4380. EDN: MQTLQN
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