AWARENESS AND TREATMENT SPECIFICS OF STATIN THERAPY IN PERSONS WITH VARIOUS CARDIOVASULAR RISK: THE STUDY ESSE-RF

S. A. Shalnova; A. D. Deev; V. A. Metelskaya; S. E. Evstifeeva; O. P. Rotar; Yu. V. Zhernakova; S. А. Boytsov; Yu. A. Balanova; N. V. Gomyranova; A. E. Imaeva; A. V. Kapustina; A. V. Kontsevaya; O. A. Litinskaya; M. N. Mamedov; G. A. Muromtseva; R. G. Oganov; E. I. Suvorova; M. B. Khudyakov; E. I. Baranova; A. O. Konradi; E. V. Shlyakhto; V. A. Ilin; R. A. Kasimov; A. A. Shabunova; K. N. Kalashnikov; O. N. Kalachikova; O. A. Kondakova; A. V. Popov; N. A. Ustinova; O. G. Azarin; N. I. Babenko; L. V. Bondartsov; E. V. Minakov; A. E. Khvostikova; G. I. Furmenko; S. V. Nedogoda; A. A. Ledyaeva; E. V. Chumachek; N. V. Kulakova; M. V. Mokshina; V. A. Nevzorova; L. V. Rodionova; N. V. Shestakova; O. A. Belova; O. A. Nazarova; S. V. Romanchuk; O. A. Shutemova; V. S. Kaveshnikov; R. S. Karpov; V. N. Serebryakova; I. A. Trubacheva; A. I. Aristov; Yu. I. Grinshtein; L. K. Danilova; A. A. Evsyukov; D. S. Kaskaeva; A. A. Kosinova; M. M. Petrova; R. R. Ruf; N. V. Topolskaya; V. V. Shabalin; E. N. Shmatova; O. L. Barbarash; G. V. Artamonova; A. E. Skripchenko; E. V. Indukaeva; T. A. Mulerova; S. A. Maksimov; N. V. Cherkass; M. V. Tabakaev; Ya. V. Danilchenko; I. R. Basyrova; E. N. Isaeva; V. Yu. Kondratenko; R. A. Libis; E. A. Lopina; D. V. Safonova; S. K. Gutnova; T. M. Gatagonova; G. V. Tolparov; S. A. Gudkova; D. V. Duplyakov; N. A. Cherepanova; A. Yu. Efanov; I. V. Medvedeva; M. A. Storozhok; V. P. Shava; S. V. Shalaev

doi:10.15829/1728-8800-2016-4-29-37

AWARENESS AND TREATMENT SPECIFICS OF STATIN THERAPY IN PERSONS WITH VARIOUS CARDIOVASULAR RISK: THE STUDY ESSE-RF

S. A. Shalnova, A. D. Deev, V. A. Metelskaya, S. E. Evstifeeva, O. P. Rotar, Yu. V. Zhernakova, S. А. Boytsov, Yu. A. Balanova, N. V. Gomyranova, A. E. Imaeva, A. V. Kapustina, A. V. Kontsevaya, O. A. Litinskaya, M. N. Mamedov, G. A. Muromtseva, R. G. Oganov, E. I. Suvorova, M. B. Khudyakov, E. I. Baranova, A. O. Konradi, E. V. Shlyakhto, V. A. Ilin, R. A. Kasimov, A. A. Shabunova, K. N. Kalashnikov, O. N. Kalachikova, O. A. Kondakova, A. V. Popov, N. A. Ustinova, O. G. Azarin, N. I. Babenko, L. V. Bondartsov, E. V. Minakov, A. E. Khvostikova, G. I. Furmenko, S. V. Nedogoda, A. A. Ledyaeva, E. V. Chumachek, N. V. Kulakova, M. V. Mokshina, V. A. Nevzorova, L. V. Rodionova, N. V. Shestakova, O. A. Belova, O. A. Nazarova, S. V. Romanchuk, O. A. Shutemova, V. S. Kaveshnikov, R. S. Karpov, V. N. Serebryakova, I. A. Trubacheva, A. I. Aristov, Yu. I. Grinshtein, L. K. Danilova, A. A. Evsyukov, D. S. Kaskaeva, A. A. Kosinova, M. M. Petrova, R. R. Ruf, N. V. Topolskaya, V. V. Shabalin, E. N. Shmatova, O. L. Barbarash, G. V. Artamonova, A. E. Skripchenko, E. V. Indukaeva, T. A. Mulerova, S. A. Maksimov, N. V. Cherkass, M. V. Tabakaev, Ya. V. Danilchenko, I. R. Basyrova, E. N. Isaeva, V. Yu. Kondratenko, R. A. Libis, E. A. Lopina, D. V. Safonova, S. K. Gutnova, T. M. Gatagonova, G. V. Tolparov, S. A. Gudkova, D. V. Duplyakov, N. A. Cherepanova, A. Yu. Efanov, I. V. Medvedeva, M. A. Storozhok, V. P. Shava, S. V. Shalaev

https://doi.org/10.15829/1728-8800-2016-4-29-37

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Abstract

Aim. To assess rate of familiarity and specifics of treatment with statins among the citizens of economically active age with various cardiovascular risk by the data from epidemiological study ESSE-RF (Epidemiology of Cardiovascular Diseases in Different Russian Federation Regions). Material and methods. In the work the data from ESSE-RF study was used, of representative selection of non-organized male and female inhabitants aged 25-64 y.o. from 13 regions, investigated during 2012-2014. Responded ~80%. The study included questionning by standard scale that included data on the anamnesis, etc. Lipid profile, including total cholesterol (TC), cholesterol of lipoproteids low and high density were measured at SSRCPM and RSPCC.

Results. Analysis of the whole selection showed that 20% of men and 32% of women knew their TC, and 13,6% and 18,2% were even familiar having increased level of TC. Part of those with high and very high risk was 31,3%, incl. men — 42,2%, women — 30,9%. Statins took ~7,0% of patients from this risk category. Effectiveness of treatment (target levels reached of low density cholesterol) in these groups of men and women was 14,4% and 4,8%, respectively.

Conclusion. The data obtained in populational study points on insufficient knowledge and low rate of statin treatment of the persons with high and very high cardiovascular risk in RF, which confirms the anxiety provoking data of registries and other studies. The data dictates necessity of development and implementation of specific educational programs for citizens, of physician improvement and availability of cheap but effective lipid-lowering medications.

Keywords

ESSE-RF study, rate of awareness, SCORE risk, total cholesterol and low density lipoproteides cholesterol, statins, treatment efficacy

About the Authors

S. A. Shalnova

National Research Center for Preventive Medicine of the Ministry of Health, Moscow
Russian Federation

A. D. Deev

National Research Center for Preventive Medicine of the Ministry of Health, Moscow
Russian Federation

V. A. Metelskaya

National Research Center for Preventive Medicine of the Ministry of Health, Moscow
Russian Federation

S. E. Evstifeeva

National Research Center for Preventive Medicine of the Ministry of Health, Moscow
Russian Federation

O. P. Rotar

Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg
Russian Federation

Yu. V. Zhernakova

Russian Cardiological Research-and-Production Complex of the Ministry of Health, Moscow
Russian Federation

S. А. Boytsov

National Research Center for Preventive Medicine of the Ministry of Health, Moscow
Russian Federation
Boytsov S. A. on behalf of ESSE-RF trial workgroup

Yu. A. Balanova