ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
https://doi.org/10.15829/1728-8800-2017-5-16-19
Abstract
Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.
Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o.
Results. Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation.
Conclusion. In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.
About the Authors
V. M. Baev
Wagner E.A. Perm State Medical University of the Ministry of Health
Russian Federation
Perm
Russian Federation
Perm
T. Yu. Agafonova
Wagner E.A. Perm State Medical University of the Ministry of Health
Russian Federation
Perm
Russian Federation
Perm
O. A. Samsonova
Wagner E.A. Perm State Medical University of the Ministry of Health
Russian Federation
Perm
Russian Federation
Perm
R. Sh. Dusakova
Wagner E.A. Perm State Medical University of the Ministry of Health
Russian Federation
Perm
Russian Federation
Perm
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Review
For citations:
Baev V.M., Agafonova T.Yu., Samsonova O.A., Dusakova R.Sh. ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION. Cardiovascular Therapy and Prevention. 2017;16(5):16-19. (In Russ.) https://doi.org/10.15829/1728-8800-2017-5-16-19
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