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Кардиоваскулярная терапия и профилактика

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АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ У ОЧЕНЬ ПОЖИЛЫХ: ЗНАЧЕНИЕ БИОЛОГИЧЕСКОГО ВОЗРАСТА

https://doi.org/10.15829/1728-8800-2017-3-87-96

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Аннотация

Популяция пожилых людей гетерогенна, и люди с одинаковым хронологическим возрастом  значительно различаются  по состоянию здоровья  и функциональному статусу. Планирование терапевтических вмешательств  у людей старческого возраста  невозможно без учета их влияния на физические и когнитивные функции человека. Несмотря  на убедительную доказанность  неблагоприятного  прогностического  значения  повышенного  артериального   давления (АД) у людей среднего  возраста, его влияние на прогноз у очень пожилых продолжает обсуждаться, равно как и вопрос, следует ли лечить  артериальную  гипертонию  (АГ)  в  старческом  возрасте, и если да, то насколько интенсивно. В статье представлены результаты наблюдательных и рандомизированных клинических исследований, которые позволяют судить о том, что не хронологический, а биологический возраст становится важным критерием для принятия решения о тактике лечения АГ у пожилых людей. В статье подробно  обсуждаются  механизмы,  участвующие в  регуляции  АД, а также влияние АД на риск заболеваемости и смертности у пациентов старческого возраста. Приводятся выдержки из существующих рекомендации  по антигипертензивной терапии, а также обсуждаются вопросы лечения АГ у пациентов старшего возраста, требующие дальнейших исследований.

Об авторах

Ю. В. Котовская
ФГБОУ ВО “Российский национальный исследовательский медицинский университет им. Н. И. Пирогова” Министерства здравоохранения Российской Федерации — ОСП “Российский геронтологический научно-клинический центр”; ФГАОУ ВО “Российский университет дружбы народов” Министерства образования и науки Российской Федерации
Россия

Котовская Юлия Викторовна — доктор медицинских наук РНИМУ им. Н. И. Пирогова, профессор, зав. кафедрой кардиологии и персонифицированной медицины ФПК МР Ми, руководитель лаборатории сердечно-сосудистого старения РУДН.

Москва



О. Н. Ткачева
ФГБОУ ВО “Российский национальный исследовательский медицинский университет им. Н. И. Пирогова” Министерства здравоохранения Российской Федерации — ОСП “Российский геронтологический научно-клинический центр”
Россия

Ткачева Ольга Николаевна — доктор медицинских наук, профессор, директор РГНЦ,  зав.  кафедрой болезней старения  РНИМУ им. Н.И. Пирогова.

Москва



Н. К. Рунихина
ФГБОУ ВО “Российский национальный исследовательский медицинский университет им. Н. И. Пирогова” Министерства здравоохранения Российской Федерации — ОСП “Российский геронтологический научно-клинический центр”
Россия

Рунихина Надежда Константиновна — доктор медицинских наук, заместитель директора Российского геронтологического научно-клинического центра.

Москва



В. С. Остапенко
ФГБОУ ВО “Российский национальный исследовательский медицинский университет им. Н. И. Пирогова” Министерства здравоохранения Российской Федерации — ОСП “Российский геронтологический научно-клинический центр”
Россия

Остапенко Валентина Сергеевна — ассистент кафедры болезней старения факультета дополнительного образования, врач-гериатр.

Москва



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Для цитирования:


Котовская Ю.В., Ткачева О.Н., Рунихина Н.К., Остапенко В.С. АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ У ОЧЕНЬ ПОЖИЛЫХ: ЗНАЧЕНИЕ БИОЛОГИЧЕСКОГО ВОЗРАСТА. Кардиоваскулярная терапия и профилактика. 2017;16(3):87-96. https://doi.org/10.15829/1728-8800-2017-3-87-96

For citation:


Kotovskaya Y.V., Tkacheva О.N., Rukikhina N.К., Ostapenko V.S. ARTERIAL HYPERTENSION IN A VERY OLD: SIGNIFICANCE OF THE BIOLOGICAL AGE. Cardiovascular Therapy and Prevention. 2017;16(3):87-96. (In Russ.) https://doi.org/10.15829/1728-8800-2017-3-87-96

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