GENDER SPECIFICS OF STRUCTURAL AND FUNCTIONAL PARAMETERS OF VESSELS IN RELATION TO PSYCHOEMOTIONAL FACTORS IN ALMOST HEALTHY INDIVIDUALS
https://doi.org/10.15829/1728-8800-2014-3-36-40
Abstract
Aim. To study gender specifics of structural and functional parameters of brachiocephal arteries with the relation to psychoemotional factors in almost healthy individuals.
Material and Methods. Overall 107 almost healthy economically active individuals included from organized population (46 male, 61 female), with the average age 43,4±10,8 y. All participants underwent psychological testing that included questionnaires: Spolberger-Khanin test, depression evaluation scale by the Center for Epidemiological Studies, visualanalogue scale (modified Dembo-Rubinstein), the social frustration level, social adaptation test by Holmes-Rey, ultrasound scanning of brachiocephal arteries with evaluation of local rigidity parameters.
Results. There were significant gender differences found for the vessel wall structural and functional parameters. Average values of systolic and diastolic diameters, total common carotid artery wall thickness were higher in males, but the rigidity index - in women. Prevalence of personal anxiety and clinically significant stress estimates by the Holmes-Rey scale was significantly higher in women, 75% and 36%, resp. In both groups the association of psycho-emotional factors and vessel parameters was found. But for men there was independent relation of reactive and personal anxiety with the thickness of “intima-media” and in women – correlation of depression and vessel wall compliance.
Conclusion. The results direct to the need for further research of novel methods for complex primary prophylaxy of stress-induced remodeling of vessels with the connection to psychoemotional and gender specifics.
About the Authors
O. Yu. Bastrikov
SBEI HPE “South-Ural State Medical University” of the Ministry of Health. Chelyabinsk, Russia
Russian Federation
Russian Federation
V. V. Belov
SBEI HPE “South-Ural State Medical University” of the Ministry of Health. Chelyabinsk, Russia
Russian Federation
Russian Federation
E. A. Grigoricheva
SBEI HPE “South-Ural State Medical University” of the Ministry of Health. Chelyabinsk, Russia
Russian Federation
Russian Federation
References
1. Kiseleva MG. Psychological factors and course of cardio-vascular diseases. National Psychological J 2012; 1 (7): 124–30. Russian (Киселева М. Г. Психологические факторы и течение сердечно-сосудистых заболеваний. Национальный психологический журнал 2012; 1 (7): 124–30).
2. Sumin AN, Sumina LJu, Barbarash NA. Stressful hemodynamic changes in type D personality in healthy young adults. Cardiovascular Therapy and Prevention 2012; 11 (3): 70–6. Russian (Сумин А. Н., Сумина Л. Ю., Барбараш Н. А. Стрессорные изменения гемодинамики при типе личности Д у здоровых лиц молодого возраста. Кардиоваскулярная терапия и профилактика 2012; 11 (3): 70–6).
3. Shavrin AP, Hovaeva JaB., Golovskoj BV. The value of psycho-emotional factors in the development of immune deficiency, infection with the organism and changes of the vascular wall in otherwise healthy individuals with risk factors. Cytokines and Inflammation 2010; 9 (4):23–7. Russian (Шаврин А. П., Ховаева Я. Б., Головской Б. В. Значение психоэмоциональных факторов в развитии иммунной недостаточности, инфицировании организма и изменении сосудистой стенки у практически здоровых лиц с факторами риска. Цитокины и воспаление 2010; 9 (4): 23–7).
4. Poli A, Tremoli E, Colombo A, et al. Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients: a new model for the quantification and follow-up of pre-clinical atherosclerosis in living human subjetcs. Atherosclerosis 1988; 70: 253–61.
5. Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27 (21): 2588–605.
6. Davidovich IM, Vinokurova IG, Porotikova EV. Vascular autoregulation and indicators of vascular stiffness in hypertensive patients younger: gender differences and the effect of antihypertensive therapy. Problems of Women’s Health 2011; 6 (2): 29–34. Russian (Давидович И. М., Винокурова И. Г., Поротикова Е. В. Ауторегуляция сосудистого русла и показатели жесткости сосудов у больных артериальной гипертензией молодого возраста: гендерные особенности и влияние антигипертензивной терапии. Проблемы женского здоровья 2011; 6 (2): 29–34).
7. Dzizinskij AA, Protasov KV. Arterial stiffness as a new factor in the prognosis of hypertension (review). Bulletin of the VSNC SO RAMN 2006; 6: 209–15. Russian (Дзизинский А. А., Протасов К. В. Артериальная жесткость как новый фактор оценки прогноза артериальной гипертонии (обзор литературы). Бюллетень ВСНЦ СО РАМН 2006; 6: 209–15).
8. Shimbo D, Chaplin W, Akinola O, et al. Effect of anger provocation on endotheliumdependent and — independent vasodilation. Am J Cardiol 2007; 99: 860–3.
9. von Kаnel R, Mills P, Fainman C, et al. Effects of psychological stress and psychiatric disorders on blood coagulation and fibrinolysis: a biobehavioral pathway to coronary artery disease? Psychosom Med 2001; 63: 531–44.
10. Schwartz A, Gerin W, Davidson K, et al. Toward a causal model of cardiovascular rresponses to stress and the development of cardiovascular disease. Psychosom Med 2003; 65: 22–35.
11. Kirichuk VF, Olenko ES, Sachkov SV, et al. Psychophysiological aspects of endothelial dysfunction in clinically healthy young adults. Russian medical-biological messenger Acad. I. P. Pavlov 2009; 2: 94–9. (Киричук В. Ф., Оленко Е. С., Сачков С. В. и др. Психофизиологические аспекты дисфункции эндотелия у клинически здоровых лиц молодого возраста. Российский медико-биологический вестник им. академика И. П. Павлова 2009; 2:94–9).
12. Glassman A. Depression and cardiovascular comorbidity. Dialogues Clin Neumsci 2007; 9: 9–17.
13. Groshev I. Genomics of mental illness: a study of gender and age and gender. Physician 2012; 9: 14–7. Russian (Грошев И. Геномика психических заболеваний: исследование половозрастных и гендерных аспектов. Врач 2012; 9: 14–7).
Review
For citations:
Bastrikov O.Yu., Belov V.V., Grigoricheva E.A. GENDER SPECIFICS OF STRUCTURAL AND FUNCTIONAL PARAMETERS OF VESSELS IN RELATION TO PSYCHOEMOTIONAL FACTORS IN ALMOST HEALTHY INDIVIDUALS. Cardiovascular Therapy and Prevention. 2014;13(3):36-40. (In Russ.) https://doi.org/10.15829/1728-8800-2014-3-36-40
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