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Кардиоваскулярная терапия и профилактика

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ПРИМЕНЕНИЕ МЕТОДА СЕКВЕНИРОВАНИЯ ЭКЗОМОВ ДЛЯ ДИАГНОСТИКИ ПРЕДРАСПОЛОЖЕННОСТИ К КОМПЛЕКСНЫМ ЗАБОЛЕВАНИЯМ В ПРОФИЛАКТИЧЕСКОЙ МЕДИЦИНЕ

https://doi.org/10.15829/1728-8800-2013-6-24-28

Полный текст:

Аннотация

Развитие профилактической медицины в XXI веке, по-видимому, невозможно без использования индивидуальных генетических данных пациента. Генодиагностика в настоящий момент служит золотым стандартом в диагностике моногенных заболеваний. В последние годы активно изучаются генетические факторы, влияющие на развитие комплексных (мультифакториальных) заболеваний, таких как ишемическая болезнь сердца, гипертоническая болезнь и т.д. Данный обзор посвящен анализу возможности выявления новых генетических факторов наследственности комплексных заболеваний, полученных при секвенировании экзомов пациентов. 

Об авторах

Н. В. Щербакова
ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва
Россия
лаборант исследователь лаборатории молекулярной генетики


А. Н. Мешков
ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва
Россия

руководитель лаборатории

Тел.: 8 (901) 512–12–71 



С. А. Бойцов
ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва
Россия
директор, руководитель отдела клинической кардиологии и молекулярной генетики


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Для цитирования:


Щербакова Н.В., Мешков А.Н., Бойцов С.А. ПРИМЕНЕНИЕ МЕТОДА СЕКВЕНИРОВАНИЯ ЭКЗОМОВ ДЛЯ ДИАГНОСТИКИ ПРЕДРАСПОЛОЖЕННОСТИ К КОМПЛЕКСНЫМ ЗАБОЛЕВАНИЯМ В ПРОФИЛАКТИЧЕСКОЙ МЕДИЦИНЕ. Кардиоваскулярная терапия и профилактика. 2013;12(6):24-28. https://doi.org/10.15829/1728-8800-2013-6-24-28

For citation:


Shcherbakova N.V., Meshkov A.N., Boytsov S.A. EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE. Cardiovascular Therapy and Prevention. 2013;12(6):24-28. (In Russ.) https://doi.org/10.15829/1728-8800-2013-6-24-28

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)