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Risk factor structure and relative prevalence of pathological alterations in arterial hypertension patients of various age groups

Abstract

Aim. To study risk factor (RF) structure and relative prevalence of pathological alterations (RPPA) in arterial hypertension (AH) patients from various age groups. Material and methods. Main group included 70 AH patients, control group – 47 individuals with normal blood pressure (BP). Mean age was 55.2±13.67 years and 53.7±13.45, respectively. In all participants, anamnestic, hemodynamic, anthropometric, and biochemical parameters were assessed. Both groups were divided into three age intervals: <35 years; 35-55 years; >55 years. At first, the parameters assessed were compared in each age interval. Then RPPA of these parameters was assessed in main and control groups. Results. Under age of 35, AH development was significantly influenced by family predisposition (FP) and abdominal obesity (AO); in 35-55 years, it was influenced by FP, AO and high level of total cholesterol (TCH); over 55 years, it was influenced by AO and high TCH level. All anthropometric, morphological, functional, and biochemical parameters studied had greater RPPA in main group than in control group, in patients under 35; in 35-55 year-olds, the tendency was similar, with insulin resistance index as an exception; after 55 years, the exceptions were pulse Conclusion. Among traditional cardiovascular event RF, only AO was a universal AH development RF for all age groups. At the same time, the study results should be regarded as preliminary.

About the Authors

A. M. Urinsky
Russian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development. Moscow
Russian Federation


R. L. Kuznetsov
Russian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development. Moscow
Russian Federation


Yu. M. Pozdnyakov
Russian Cardiology Scientific and Clinical Complex, State Federal Agency for Health and Social Development. Moscow
Russian Federation


S. A. Boytsov
Moscow Regional Cardiology Center. Zhukovsky
Russian Federation


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Review

For citations:


Urinsky A.M., Kuznetsov R.L., Pozdnyakov Yu.M., Boytsov S.A. Risk factor structure and relative prevalence of pathological alterations in arterial hypertension patients of various age groups. Cardiovascular Therapy and Prevention. 2006;5(4):33-40. (In Russ.)

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)