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Cardiovascular Therapy and Prevention

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Low-molecular heparins in thrombolytic therapy of myocardial infarction patients

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Abstract

Currently, parenteral anticoagulant therapy is considered a standard addition to thrombolytic treatment (TLT) in myocardial infarction (MI). This review analyses the results of the clinical trials demonstrating the benefits of subcutaneous low-molecular heparin enoxaparin therapy (one week before 48-hour intravenous infusion of unfractionated heparin). This evidence influenced the modern views on optimal heparin therapy in TLT-based coronary revascularisation.

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Yavelov I.S. Low-molecular heparins in thrombolytic therapy of myocardial infarction patients. Cardiovascular Therapy and Prevention. 2009;8(6):111-122. (In Russ.)

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)