Ten-year dynamics of risk factors and total cardiovascular risk in а cohort of male intellectual workers
Abstract
Aim. To study the prevalence of cardiovascular disease (CVD) risk factors (RFs), to evaluate the dynamics of RFs and total CVD risk during 10-year ambulatory follow-up of a cohort of male intellectual workers.
Material and methods. The study included 174 males (mean age 48,9±4,9 years), initially free from diabetes mellitus (DM) or coronary heart disease (CHD). Seven main CVD RFs were studied - family CVD history, hypercholesterolemia (HCH), arterial hypertension (AH), overweight and obesity, smoking, excessive alcohol consumption - as well as two additional RFs - elevated heart rate (HR) and electrocardiography signs of left ventricular hypertrophy (LVH). Ten-year dynamics of most prevalent RFs and their combinations was evaluated. Ten-year dynamics of total CVD risk was assessed by European SCORE model.
Results. During 10-year follow-up, the prevalence of main CVD RFs significantly increased: for AH by 40,2 %, for overweight and obesity - by 35,6 % and 9,2 %, respectively. Prevalence of HCH reduced by 5,8 %, smoking - by 50 %, and excessive alcohol consumption - by 8,6 %. The number of people with elevated HR and ECG signs of LVH had doubled. In 13,8 %, Type 2 DM had developed. At baseUne, isolated CVD RFs were observed in 20,7 %, 10 years later - in 13,2 % only In 10 years, the number of individuals with low total risk decreased by 3 times, while the number of persons with high or very high total CVD risk increased by 2 and 7,8 times, respectively.
Conclusion. Different levels of psychological and physical stress in intellectual and manual workers are reflected by different patterns of CVD RF prevalence. High psycho-emotional stress levels significantly increase AH prevalence. In combination with other RFs, it results in total CVD risk increase, which could not be explained by age-related changes only
About the Authors
N. A. Chepurina
State Research Center for Preventive Medicine, Federal Agency on High Medical Technologies. Moscow
Russian Federation
Russian Federation
M. N. Mamedov
State Research Center for Preventive Medicine, Federal Agency on High Medical Technologies. Moscow
Russian Federation
Russian Federation
A. D. Deev
State Research Center for Preventive Medicine, Federal Agency on High Medical Technologies. Moscow
Russian Federation
Russian Federation
N. V. Кisseleva
State Research Center for Preventive Medicine, Federal Agency on High Medical Technologies. Moscow
Russian Federation
Russian Federation
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Review
For citations:
Chepurina N.A., Mamedov M.N., Deev A.D., Кisseleva N.V. Ten-year dynamics of risk factors and total cardiovascular risk in а cohort of male intellectual workers. Cardiovascular Therapy and Prevention. 2008;7(7):27-33. (In Russ.)
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