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Extemal counter-pulsation effects on left ventricular myocardial perfusion in patients with coronary heart disease

Abstract

Aim. To assess the effects of enhanced external counter-pulsation (EECP) on left ventricular (LV) myocardial perfusion.

Material and methods. In total, 26 patients with coronary heart disease (CHD), stable angina, Functional Class (FC) I-IV, were treated with EECP. Treatment course included 35 one-hour procedures. At baseline and after EECP treatment, all patients underwent 99m-Tc-MIBI scintigraphy (single photon emission computed tomography, SPECT) at rest and during stress test.

Results. After EECP treatment, perfusion defect severity assessed by SPECT at rest had significantly reduced (p<0,01). Pre- and post-EECP perfusion defect areas were 18,0±13,6 % and 17,2±15,7 %, respectively (p>0,05); pre- and post-EECP perfusion defect severity - 347,3±282,8 and 310±266,0 std, respectively (p<0,01). No significant dynamics of perfusion defect area or severity was observed for stress EECP.

Conclusion. EECP treatment was associated with improved LV myocardial perfusion in CHD patients.

About the Authors

I. V. Sergienko
Russian Cardiology Scientific and Clinical Complex, Federal Agency on High Medical Technologies. Moscow
Russian Federation


S. A. Gabrusenko
Russian Cardiology Scientific and Clinical Complex, Federal Agency on High Medical Technologies. Moscow
Russian Federation


V. V. Malakhov
Russian Cardiology Scientific and Clinical Complex, Federal Agency on High Medical Technologies. Moscow
Russian Federation


M. E. Bugriy
Russian Cardiology Scientific and Clinical Complex, Federal Agency on High Medical Technologies. Moscow
Russian Federation


V. B. Sergienko
Russian Cardiology Scientific and Clinical Complex, Federal Agency on High Medical Technologies. Moscow
Russian Federation


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Review

For citations:


Sergienko I.V., Gabrusenko S.A., Malakhov V.V., Bugriy M.E., Sergienko V.B. Extemal counter-pulsation effects on left ventricular myocardial perfusion in patients with coronary heart disease. Cardiovascular Therapy and Prevention. 2008;7(7):85-90. (In Russ.)

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)