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Кардиоваскулярная терапия и профилактика

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Этиологические и патогенетические факторы первичной артериальной гипертонии

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Аннотация

В последние десятилетия накопилось достаточно данных, свидетельствующих, что артериальная гипертония (АГ) является полигенно наследуемой патологией. При этом недостаточная экскреция почками поваренной соли (ПС), генетически обусловленная или приобретенная (болезни, старение, ожирение и др.), является центральным механизмом патогенеза АГ. Развитие АГ необходимо рассматривать как компенсаторную реакцию, направленную на увеличение экскреции почками ПС и нормализацию объема гомеостаза и циркулирующей крови.

Об авторах

В. С. Волков
ГОУ ВПО Тверская государcтвенная медицинская академия Росздрава. Тверь
Россия
зав.кафедрой госпитальной терапии


А. П. Тофило
ГОУ ВПО Тверская государcтвенная медицинская академия Росздрава. Тверь
Россия
доцент кафедры усовершенствования врачей


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Для цитирования:


Волков В.С., Тофило А.П. Этиологические и патогенетические факторы первичной артериальной гипертонии. Кардиоваскулярная терапия и профилактика. 2010;9(7):105-111.

For citation:


Volkov V.S., Tofilo A.P. Aetiological and pathogenetic factors of primary arterial hypertension. Cardiovascular Therapy and Prevention. 2010;9(7):105-111. (In Russ.)

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